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MICROBIAL DATING PROFILES - VOTE! My 1st yr Medical Laboratory Technology students created some microbial dating profiles! The winners get the chance to redeem some lab marks, so please help out by voting. I will post them in this thread with the voting options. /1 #medlabtwitter

After 10+ fantastic years in Madison, it is bittersweet to announce that my lab and I are moving to Test Account soon. I am so grateful to everyone at UW–Madison Biochem and Morgridge Institute for their support and guidance. Stay healthy, and come visit us in St. Louis! medicine.wustl.edu/news/pagliarin…

A bit of good news in these strange times: I’m thrilled to announce that I’ll be starting my lab in the department of Biochemistry and Molecular Biophysics @WUSTL this summer. 1/n

Happy to share this Cell Metabolism review from our group. Andrew Sung, Brendan Floyd, and I hope it has some useful lessons of how large-scale analyses can lead to focused mechanistic hypotheses and help functionalize orphan proteins. #mitochondria cell.com/cell-metabolis…

First day in the Niemi Lab. We are recruiting - come help us fill all of this newly renovated lab space! More details on who we are and what we do at niemilab.com. #mitochondria #WashU

We are excited to share a collaborative pre-print that describes an unexpected connection between loss of mitochondrial function in the liver and suppression of the immune system. How did it start and where did we end up? /1 biorxiv.org/content/10.110…

I am excited to post our new manuscript on CoQ pathway manipulation, led by Nathan Murray. Congrats to Nate and our multiple collaborators key collaborators! Small Molecule Modulation of the Archetypal UbiB protein COQ8 biorxiv.org/content/10.110…

1/now that Elon Musk is taking over Twitter I am pressed into action as I am not sure I will stay on this platform much longer…. This story started in 2015 when I still did lab work…

Our new study, led by Alaumy Joshi, shows a critical requirement of cardiolipin (CL) for the stability of the mitochondrial Mg channel. This study uncovers a potentially novel role of Mg in the pathology of Barth syndrome, a genetic disorder of CL metabolism. academic.oup.com/hmg/advance-ar…

Happy to share our new mitochondrial proteome research review out today in Nature Reviews Molecular Cell Biology led by Zak Baker and Patrick Forny. The field has come a long way in the past 20 years, yet plenty of exciting new things to do! nature.com/articles/s4158… rdcu.be/dnmm3 #Mitochondria

Everything you always wanted to know about the mitochondrial proteome but were too afraid to ask. From classic enzymology to novel mass spectrometry techniques. I'm so happy to finally have this out there!

Excited to share our new discovery of a mitochondrial isoprene transporter published today in Nature Cell Biology and led by Jonathan Tai! Interesting example of transporter dual functionality. #Mitochondria nature.com/articles/s4155…

Very (very!!) happy to share our latest publication, "PPTC7 maintains mitochondrial protein content by suppressing receptor-mediated mitophagy", out today in Nature Communications. 1/n nature.com/articles/s4146…

CoQ10 is a very hydrophobic molecule with poor bioavailability. In this new study, led by Laura Steenberge, we build on prior work to show that the much more soluble CoQ4 is sufficient to rescue diverse CoQ functions and can be targeted to mitochondria. doi.org/10.1016/j.jbc.…

Mitochondrial complex I construction relies on a patchwork of poorly defined "assembly factors." In work led by Andrew Sung, we used deep mutational scanning to elucidate NDUFAF6 function and predict variant pathogenicity. Taylor Lab Charlotte Alston nature.com/articles/s4225…