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Fibroblast and myofibroblast activation in normal tissue repair and fibrosis nature.com/articles/s4158…

Neuro-mesenchymal interaction mediated by a β2 adrenergic-nerve growth factor feedforward loop promotes colorectal cancer progression. aacrjournals.org/cancerdiscover…

Excited to share the line-up of the Ovarian Cancer Research Syndicate speakers for the fall. Exciting topics from Rising Stars, early career investigators, and established faculty. Join us! Tullia Bruno, PhD Powell-Drescher Ovarian Cancer Research Foundation Daniel Powell Lab @ UPENN Katherine Aird Ben Bitler Emil Lou, MD, PhD, FACP Analisa DiFeo

Our new #paper is out in Nature Immunology. Applying #spatial transcriptomics at subcellular resolution to 130 ovarian #cancer tumors, followed by data-driven experimental design and high content #CRISPR screens to map immune evasion in ovarian cancer nature.com/articles/s4159… (1/15)

Carcinoma-associated mesenchymal stem cells promote ovarian cancer heterogeneity and metastasis through mitochondrial transfer: Cell Reports cell.com/cell-reports/f…

Classifying cancer-associated fibroblasts—The good, the bad, and the target: Cancer Cell cell.com/cancer-cell/fu…

Another interesting read from this week Cancer Cell! Fibrotic response to anti-CSF-1R therapy potentiates glioblastoma recurrence: cell.com/cancer-cell/fu…

📢 Hot off the press! CAFs are major regulators of the immune tumor microenvironment. In our new review we dissect a fascinating aspect of this regulation: CAF-induced physical constraints controlling T cell state and localization in solid tumours nature.com/articles/s4156…

We are looking for an enthusiastic and skilled Postdoc to study the roles of CAF metabolism in the immune-tumour microenvironment using cutting-edge spatial MS proteomics workflows and patient tissue samples. Start ASAP. crukscotlandinstitute.ac.uk/careers/postdo…

Great to be part of this special issue. Thank you very much Cancer Research for the opportunity to write about our favorite cell type 💜. A fantastic job from Gianluca Mucciolo and Wenlong Li ⭐️⭐️.

Looking forward to it! 👇🏻

📣I am very excited to announce that our lab is moving (very soon) to MD Anderson in Houston! If you share our passion for #TME #CAF #metabolism, cutting-edge #MSproteomics, and are interested to join us for a postdoc, please contact me!

The 68th Benzon Symposium report is now online in Molecular & Cellular Proteomics ! Fantastic conference that brought together top global experts in Copenhagen to translate proteomics to the clinics - from technological advances to regulatory frameworks! Matthias Mann Lab bit.ly/3AsuN3X

One of the best Symposium i have been to, lot of insights on the future of how to get to using proteomics into the clinics! Also excellent atmosphere, great discussion! Strongly encourage to ready it 👇🏻

Making space for spatial biology in the clinic Spatial transcriptomics methods have been slow to move into clinical practice, but spatial proteomics are cheaper and more scalable, and could progress faster go.nature.com/3PoWPkz

The new ZanivanLab 2.0 MD Anderson Cancer Center is growing 😃! After Fernanda G. Kugeratski joining as an Instructor since day 1, we welcome Amari Sockwell as senior research assistant. And the lab is almost functional, so…lot of new research coming soon! #TME #CAF #Proteomics #metabolism

We welcome Sieun Lee to our growing Lab MD Anderson Cancer Center with Fernanda G. Kugeratski and Amari Sockwell! Look forward to seeing where her research will drive us on understanding immune-regulatory roles of CAF metabolism in cancer

We received the cover for our recent publication in Clinical Cancer Research. This multi-institutional study offers the first systematic proteogenomic analysis of synchronous endometrial and ovarian cancers (SEOC). Read: bit.ly/4kVgq9L Lengyel Lab Melanie Weigert Matthias Mann Lab

For those interested in the role of cancer-associated fibroblasts in the tumor microenvironment, please check out our review focused on recent discoveries related to CAF biology in the context of immunotherapy, metabolism, and extracellular vesicles: authors.elsevier.com/c/1lR1I_LjpbTT…

If you are interested to learn more about CAFs , read this great mini-review by Fernanda G. Kugeratski and Emily Kay 👇🏻