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DeepPrep is a preprocessing pipeline for functional and structural MRI data from human subjects. Deep learning-based modules and an efficient workflow allow DeepPrep to handle large datasets. Jianxun Ren (find me here @jianxunren.bsky.social) Hesheng Liu nature.com/articles/s4159…

📢Out now! Xihao Li, Pradeep Natarajan, Zilin Li, Zhonghua Liu, Xihong Lin, and colleagues from NIH NHLBI present a framework for functionally-informed multi-trait rare variant analysis of biobank-scale sequencing studies. nature.com/articles/s4358… 🔓rdcu.be/d82Fx

Multiple postdoc positions available in my lab and Loïc Yengo's lab at UQ! Exciting opportunities to work on diverse statistical genetics projects. Apply here: nature.com/naturecareers/… #Genomics #StatGen #PostdocJobs

We're thrilled to share our latest publication, A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies, in Nature Computational Science. Sincerely thanks to Xihong Lin for incredible mentorship, Zilin Li, Zhonghua Liu, Pradeep Natarajan, Dr.

A fascinating new study just published online today in Nature Medicine reports an extraordinary case of an individual carrying the PSEN2 (p.Asn141Ile) mutation—a known driver of dominantly inherited Alzheimer’s disease (DIAD)—who remained cognitively healthy well into his

New paper I’m involved in out today in ⁦Science Magazine⁩ led by ⁦Eleanor Raffan⁩ ⁦GOdogs project⁩ ⁦Natalie Wallis⁩ ⁦Cambridge University⁩ Picture by ⁦Jane Goodall⁩ #obesityisnotachoice bbc.com/news/articles/…

Congratulations stephen o'rahilly (its pronounced O-RA-hill-EEE) Inst Metabolic Science-Metabolic Research Labs

2nd half-marathon.

🚨We're hiring! Come join us in Belfast at Wellcome-Wolfson Institute Experimental Medicine 🔬 We're looking for a postdoc to help uncover the mechanism behind a novel genetic cause of heart failure, funded by British Heart Foundation. Apply here👉 hrwebapp.qub.ac.uk/tlive_webrecru… Questions? Reach out via X/LinkedIn/Email! David Grieve

Well deserved! Congrats stephen o'rahilly (its pronounced O-RA-hill-EEE)!

SARS-CoV-2 variants NB.1.8.1 and XFG are spreading fast. In this new paper, we explain their high growth advantage. 1. XFG is strong in immune evasion but shows lower ACE2 binding. 2. NB.1.8.1 is very well-balanced between immune evasion and ACE2 usage. thelancet.com/journals/lanin…

One year ago, I returned to China to build my own research group from scratch. Today, I’m proud to have such a productive and capable team.

Our scMicro-C paper is out in Nature Genetics! Huge thanks to the reviewers for their valuable insights, to SunneyXie for unwavering support, and to fantastic collaborators Jiankun Zhang & Longzhi Tan. Thrilled to share this work!

Congratulations to Honggui, Jiankun, and Tan for improving the single-cell 3D genome resolution by a factor of 4 (to 5 Kb). This allowed direct visualization that multiple enhancers cluster to a particular gene promoter at the same time in a single cell. nature.com/articles/s4158…

Great work, congrats David Adams !

1/ CAPTAIN is coming! We are excited to introduce our new single-cell multimodal foundation model, CAPTAIN. 📄 Preprint: biorxiv.org/content/10.110… 💻 Code: github.com/iamjiboya/CAPT…

Such a impressive work! Congrats Vijay Sankaran and team!

Patterns and drivers of 43,617 mosaic chromosomal alterations in blood medrxiv.org/cgi/content/sh… #medRxiv