24 yrs ago, Roger Tsien et al introduced the first fluorescent biosensors based on #GFP. Today, we introduce the first acoustic biosensors based on #gasvesicles. Now it's possible to image the action of specific molecules (enzymes) in the body w/ultrasound nature.com/articles/s4158…

The final peer-reviewed version of this paper is out at ACS Synthetic Biology. Congrats again to Mohamad Abedi, @lee_chebbs and DanPiraner on this exciting advance. pubs.acs.org/doi/abs/10.102…

Join our team as a Research Technician! Perfect opportunity for graduating or recent undergraduate who wants to get additional research experience before pursuing a PhD or MD. phf.tbe.taleo.net/phf03/ats/care…

Congrats to Claire Rabut and colleagues on developing uAM, a new method to acquire biomolecular ultrasound images in a fraction of a millisecond, with simultaneous imaging of blood flow. Out today in APL AIP Publishing. aip.scitation.org/doi/10.1063/5.…

Can cells be engineered to infiltrate a tumor and blow it up from the inside? Yes, when they express #gasvesicles as seeds for ultrasound-triggered bubble cavitation! Congrats to star postdoc Avinoam Bar-Zion and team on this publication! nature.com/articles/s4156…

New year, new Acoustic Reporter Genes! 🎉 Excited to publish ARG 2.0 – much brighter, easier to express & enabling real-time imaging. ARG2.0 >> ARG1.0 (like mCherry >> original GFP) Congrats Marjorie Buss,Mengtong (Tom) Duan,Rob Hurt et al! go.nature.com/3WM2h3e Caltech HHMI

Join us! Our lab is hiring a Research Technician. Great chance to learn, contribute to science and be part of a fun team Caltech. Please RT! phf.tbe.taleo.net/phf03/ats/care…

It’s truly a fun journey throughout my PhD. It would never be possible without the support from all of you especially my two best mentors Mikhail Shapiro (same on bsky) 🇺🇦 Anupama Lakshmanan and my extraordinary mentees Ruby and Teresa. Thank you all and enjoy the manuscript!

This is a really fun collaboration with Rob Hurt and others! We hope everyone can use this and we are so excited to see how many new acoustic biomolecules this engineering platform would bring. Tell us what you are thinking and let’s make it!

It has been an amazing experience. I am really grateful to do this with all my mentors (especially Mikhail Shapiro (same on bsky) 🇺🇦), colleagues and friends. Let’s working on exciting science together!

Can you use simple diagnostic ultrasound to flip a "diffusion switch" in a hydrogel and deliver drugs? Yes, with Acoustic Percolation Switches! Congrats to Paulene Abundo, Anna Tifrea, Marjorie Buss and colleagues on this advance. biorxiv.org/content/10.110… #gasvesicles

The LA fires hit the Caltech community pretty hard, including my brilliant MD/PhD student George Daghlian, whose family lost their home. 🥹 I'm glad to be able to help, and grateful to so many friends assisting however they can! 💪 gofundme.com/f/daghlian-fam…

A big step forward for biomolecular ultrasound! 🔊 Congrats Baptiste Heiles 🔊🐭🧠, David Maresca at TU Delft and collaborators! #gasvesicles