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Autosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive development of kidney cysts. This Review discusses ADPKD diagnosed in adulthood. ja.ma/3GXwzwT

Scientists have found that tumor necrosis factor can switch macrophage efferocytosis from immunologically silent to pro-inflammatory during sepsis and systemic inflammation. Learn more in Science Immunology: scim.ag/442SmLi

Very proud of Fariha Nusrat, who presented her poster on Trem2+ macrophages in PKD today at the PKD FASEB meeting!

Review Article by Alessandra Boletta and Michael J. Caplan (Yale University). Physiologic mechanisms underlying polycystic #kidney disease ow.ly/ulil50Wj8pi #PolycysticKidneyDisease Ospedale San Raffaele

Huge congratulations to the first post doc in my lab, Sarah Jane , who is starting her lab OUHSC Division of Nephrology OU College of Medicine this week!

The 2026 RFAs for grant and fellowship awards from PKD Foundation are out! Grant:pkdcure.org/research/grant… Fellowship:pkdcure.org/research/fello… LOIs are due August 11. Send us your best ideas!!

Rethinking TREM2 as a target for Alzheimer’s disease after the INVOKE-2 trial failure | Nature Medicine nature.com/articles/s4159…

Opposing roles of microglial and macrophagic C3ar1 signaling in stress-induced synaptic and behavioral changes | Molecular Psychiatry nature.com/articles/s4138…

ZEB2 is a master switch controlling the tumor-associated macrophage program dlvr.it/TLwFvT

Regulating the fate of tumor-associated macrophages dlvr.it/TLxwYB

Love this! Physiological and injury-induced microglial dynamics across the lifespan: Cell Reports cell.com/cell-reports/f…

Excited to share our recent paper showing rescue of HFpEF phenotype by tVNS through reduction of CCR2 CRM, and change of their profile toward a proreparative state @circres Kurt zimmerman Maria Toumpourleka Sumanth Prabhu, MD Usman Baber Pilar Alcaide, PhD Joseph hill ahajournals.org/doi/abs/10.116…

1/ 🧬 Exciting news! Our group just published our study on using serum proteomics to predict disease progression in #ADPKD (Autosomal Dominant Polycystic Kidney Disease) 🔬 — enhancing risk stratification beyond currently available models 🎯 rdcu.be/exbNq

Congratulations Daniyal!!

Happy to share our latest paper on DC ontogeny! nature.com/articles/s4159… Congratulations to the team and to Dr Zhaoyuan Liu from the Shanghai Institute of Immunology!