🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

A research team led by Dan Theodorescu, the director of Cedars-Sinai Cancer in Los Angeles, is using AI to isolate more effective biomarkers than the CA 19-9 test to track & predict pancreatic cancer progression. h/t Let's Win Pancreatic Cancer 💜 #pancsm. letswinpc.org/research/ai-fi…

Thank you Journal of Clinical Investigation for this opportunity to write this review focusing on epigenetic regulation of tumor immunity.

Enjoyed participating in this fantastic session chaired by ⁦Aleks Skardal⁩ Shay Soker and Damian Hutchins at #TERMIS2024 ⁦TERMIS-AM⁩

We love to see our Scholars meet up at conferences and extend their conversations!

Congratulations, Kun-Hsing Yu !

Thanks Cancer Research for this opportunity to write the commentary highlighting a fantastic paper from Cell “Macrophage-mediated myelin recycling fuels brain cancer malignancy” by Dr. Leila Akkari and colleagues. aacrjournals.org/cancerres/arti…

Here is our latest paper now online Leukemia Journal. nature.com/articles/s4137…

Excited to share our paper just accepted by Journal of Clinical Investigation. We reveal a new macrophage-microglia interplay in GBM and develop a powerful therapeutic approach targeting them. jci.org/articles/view/…

Excited to share our review: “Immunotherapy for GBM: current state, challenges, and future perspectives ", just published in @Cellular & Molecular Immunology rdcu.be/dW19V

Just in time for #ASH24, our latest is online: nature.com/articles/s4159…

Congratulations to our Director Dan Theodorescu!!

Congratulations on the move to Stanford!

New research finds that a ketogenic diet enhances CAR T Cell antitumor function via β-Hydroxybutyrate ft. Shan Liu, @MaayanLevy_Lab (Penn Microbiology), Puneeth Guruprasad (Penn Medicine), Marco Ruella & Elise Chong (Penn Medicine - Abramson Cancer Center) tinyurl.com/4tw6eddy

Here's a new preprint from our group. This manuscript continues our efforts to understand the mechanisms that distinguish fetal/juvenile versus adult hematopoiesis to better understand pediatric blood diseases. biorxiv.org/content/10.110…

Congratulations to Scholar, @MaayanLevy_Lab!

Connecting the dots for the future of cancer research! This year’s CSVCC ACERT Workshop brought together insightful talks, tours, and hands-on whiteboarding sessions. Grateful to all who contributed their expertise and ideas! #convergentscience #scholars #cancer #militaryhealth

Happy to share our work out at Journal of Clinical Investigation We identified a new tumor-macrophage interaction contributing to GBM progression/immunosuppression and found that targeting the symbiosis sensitizes GBM to immunotherapy. Huge thanks to editors and reviewers. jci.org/articles/view/…

Improving immunotherapy in glioblastoma! Peiwen Chen & team Cleveland Clinic discover targeting legumain—which promotes infiltration of tumor-associated macrophages via the GSK3β/STAT3 pathway—has anti-tumor effects and improves immunotherapy in preclinical GBM models:

Disrupting cell communication in glioblastoma— Peiwen Chen and team Cleveland Clinic discover GPNMB mediates bidirectional communication between GBM stem cells and tumor-associated macrophages and microglia: insight.jci.org/articles/view/…

A great collaboration with my friend Jun Qi Lab. We screened a small molecule library targeting epigenetic regulators curated by Jun’s team using our dual reporter system. The ensuing mechanistic work required innovative chemical and rigorous molecular biology.