
Hubrecht Institute
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http://www.hubrecht.eu 30-06-2014 14:37:45
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Super happy to see this heroic effort by Dimitri Fabrèges and Bernat Corominas out! Via a quantitative atlas of the developmental trajectories of dozens of embryos, we can see how robust shapes and fates arise from highly stochastic cellular processes! science.org/doi/10.1126/sc… 1/n

A team from the Organoid group and Institute of Human Biology Roche has uncovered nutrient sensors on gut hormone-producing cells using organoids. The characterization of these sensors will help in treating metabolic & gut motility disorders. Joep Beumer Hans Clevers hubrecht.eu/intestinal-nut…


Congratulations to all researchers on this great new paper in Science Magazine, including Joep Beumer @geurts_maarten Veerle Geurts Ninouk Daniel Krueger Jens Puschhof, in collaboration with Roche Institute of Human Biology Maastricht University UMC Utrecht

Researchers from the Organoid group have developed a new organoid model to study the origin of colorectal cancer. The researchers studied the sequential accumulation of mutations contributing to tumor formation. Hans Clevers Tomohiro Mizutani Read more here: hubrecht.eu/organoid-color…



🧬New research published Nature Communications reveals how cells fix damaged DNA. Researchers from the @kind_jop group mapped repair proteins and show how they form 'hubs,' to coordinate repairs, almost like a 'repair café'. Learn more: hubrecht.eu/dna-repair-pro… #DNARepair #SingleCell

Researchers from The Clevers Lab created an organoid that mimics the human fetal pancreas. Unlike previous models, this organoid has all three key cell types. They also identified the stem cell that develops into these cells. Curious? hubrecht.eu/researchers-cr… Amanda Andersson Rolf Roche



📢New human fetal pancreatic organoid model generates all three key cell types of the pancreas. New paper in Cell by Amanda Andersson Rolf , Hans Clevers and collaborators. See the article here: sciencedirect.com/science/articl…


Congratulations to dr. Yasmine El Azhar, who successfully defended her thesis: Notch signalling dynamics during mouse development and homeostasis. She developed a mouse model to visualize real-time Hes1 oscillations in single cells Ina Sonnen group. hubrecht.eu/phd-defense-ya…



How reliably is the epigenome passed from one cell to its daughter cells? Alexander van Oudenaarden, Jeroen van den Berg, Anja Groth 🇺🇦 & @Lleonie received a Novo Nordisk Foundation grant to answer this question, which will lead to new strategies to prevent disease and combat aging hubrecht.eu/novo-nordisk-e…


Researchers from BakkersLab have successfully repaired damaged mouse hearts using a protein from zebrafish. This study marks a promising step toward regenerative therapies to prevent heart failure. Read more hubrecht.eu/zebrafish-prot… Dennis de Bakker Mara Bouwman Jeroen Bakkers


