Charlie McLeod (@_charliemcleod) 's Twitter Profile
Charlie McLeod

@_charliemcleod

ID: 1245671725351591937

calendar_today02-04-2020 11:17:43

71 Tweet

48 Followers

225 Following

Eric Topol (@erictopol) 's Twitter Profile Photo

Just published at nature The title tells the story for tens of million Americans "Limited cross-variant immunity from #SARSCoV2 Omicron without vaccination" nature.com/articles/s4158… The Ott Lab Gladstone Institutes UC San Francisco

World Health Organization (WHO) (@who) 's Twitter Profile Photo

Progress on the Sustainable Development Goal 3 - healthy lives & well-being for all - has been slow. This report talks about 4 approaches to accelerate progress by incentivizing stronger collaboration ▶️joint funding ▶️joint monitoring ▶️joint evaluation ▶️joint governance

Progress on the Sustainable Development Goal 3 - healthy lives & well-being for all - has been slow.
This report talks about 4 approaches to accelerate progress by incentivizing stronger collaboration
▶️joint funding
▶️joint monitoring
▶️joint evaluation
▶️joint governance
Eric Topol (@erictopol) 's Twitter Profile Photo

What's missed by our fixation on hospitalization and death metrics for the pandemic—the disability toll—the impact by disability-adjusted life years (DALYs) nature.com/articles/d4158… Holly Else nature #LongCovid

What's missed by our fixation on hospitalization and death metrics for the pandemic—the disability toll—the impact by disability-adjusted life years (DALYs) 
nature.com/articles/d4158…
<a href="/HollyElse/">Holly Else</a> <a href="/Nature/">nature</a> #LongCovid
Mediaplanet UKIE (@mediaplanetuk) 's Twitter Profile Photo

#ClinicalTrials2022 launches today, distributed inside the New Scientist and online at ow.ly/C15S30sjYat featuring Martin Landray with Protas #clinicaltrials #healthcaredata #clinicalresearch

#ClinicalTrials2022 launches today, distributed inside the <a href="/newscientist/">New Scientist</a> and online at ow.ly/C15S30sjYat featuring <a href="/MartinLandray/">Martin Landray</a> with Protas

#clinicaltrials  #healthcaredata  #clinicalresearch
The BMJ (@bmj_latest) 's Twitter Profile Photo

Early stage clinical evaluation is important to assess an AI system’s actual clinical performance. This guideline outlines key items that should be reported in early stage clinical studies of AI-based decision support systems in healthcare bmj.com/content/377/bm…

The Lancet (@thelancet) 's Twitter Profile Photo

Why do some health issues receive a great deal of attention and resources while others remain neglected? On the cover, quote from a new Lancet Series examining the interplay between politics, power, and health: hubs.li/Q01bNzVm0

Why do some health issues receive a great deal of attention and resources while others remain neglected?

On the cover, quote from a new Lancet Series examining the interplay between politics, power, and health: hubs.li/Q01bNzVm0
bioRxiv Immunology (@biorxiv_immuno) 's Twitter Profile Photo

Reduced Neutralization of SARS-CoV-2 Omicron Variant in Sera from SARS-CoV-1 Survivors after 3-dose of Vaccination biorxiv.org/cgi/content/sh… #biorxiv_immuno

bioRxiv Immunology (@biorxiv_immuno) 's Twitter Profile Photo

Anti-chemokine antibodies after SARS-CoV-2 infection correlate with favorable disease course biorxiv.org/cgi/content/sh… #biorxiv_immuno

Jeremy Faust MD MS (ER physician) (@jeremyfaust) 's Twitter Profile Photo

Of known respiratory viruses, only Covid-19 has ever killed more than 100 US children in a month in the modern era (for as far back as I can track into the 1990s); it did so three times during the Delta and Omicron alone👇 insidemedicine.bulletin.com/delta-and-omic…

Of known respiratory viruses, only Covid-19 has ever killed more than 100 US children in a month in the modern era (for as far back as I can track into the 1990s); it did so three times during the Delta and Omicron alone👇
insidemedicine.bulletin.com/delta-and-omic…
Eric Topol (@erictopol) 's Twitter Profile Photo

An Omicron (BA.1) specific booster hits immunologic and safety endpoints in a Phase 2/3 trial compared with ancestral strain booster, expected to be available in late summer/fall; Moderna release, attached

An Omicron (BA.1) specific booster hits immunologic and safety endpoints in a Phase 2/3 trial compared with ancestral strain booster, expected to be available in late summer/fall; <a href="/moderna_tx/">Moderna</a> release, attached
CEPI (@cepivaccines) 's Twitter Profile Photo

Teenagers aged 12-15 are being recruited for a new study led by University of Oxford with National Institute for Health and Care Research to investigate the performance of reduced and mix-and-match #COVID19 booster shots. CEPI is fully funding the study, known as the Com-COV 3 trial ITV News 👇 itv.com/news/meridian/…

Christopher Blyth (@chrisblyth74) 's Twitter Profile Photo

Wonderful for Michael Dymock to present the intricacies of CUSUM/PPA to detect vaccine safety signals at #CDIC2022. A great addition to improve confidence in vaccine safety and the timeliness of adverse event detection WCVID telethonkids Tom

Wonderful for <a href="/MichaelDymock2/">Michael Dymock</a> to present the intricacies of CUSUM/PPA to detect vaccine safety signals at #CDIC2022. A great addition to improve confidence in vaccine safety and the timeliness of adverse event detection <a href="/WCVID/">WCVID</a> <a href="/telethonkids/">telethonkids</a> <a href="/snelling_tom/">Tom</a>
WCVID (@wcvid) 's Twitter Profile Photo

PICOBOO needs you - join our telethonkids #COVID Booster Study! We are now recruiting adults 18+ interested in receiving their next #COVID19 vaccine as part of our #research investigating the most effective, long-term strategies for booster vaccinations telethonkids.org.au/news--events/n…

PICOBOO needs you - join our <a href="/telethonkids/">telethonkids</a> #COVID Booster Study! 
We are now recruiting adults 18+ interested in receiving their next #COVID19 vaccine as part of our #research investigating the most effective, long-term strategies for booster vaccinations 
telethonkids.org.au/news--events/n…
WCVID (@wcvid) 's Twitter Profile Photo

Huge news! A first-of-its-kind national study looking at optimal #COVID19 vaccination strategies for kids & teens will be led by telethonkids thanks to a $3.8 million #MRFF grant. Kids aged 6 - 17 can take part in Perth, Melb, Adelaide & Launceston 👇 telethonkids.org.au/news--events/n…

Huge news! A first-of-its-kind national study looking at optimal #COVID19 vaccination strategies for kids &amp; teens will be led by <a href="/telethonkids/">telethonkids</a> thanks to a $3.8 million #MRFF grant. 

Kids aged 6 - 17 can take part in Perth, Melb, Adelaide &amp; Launceston 👇
telethonkids.org.au/news--events/n…
Shamez Ladhani (@shamezladhani) 's Twitter Profile Photo

Imagine telling a parent of a 5-11 yo that #COVID19 vaccine will be 20% effective agains #SARSCoV2 after 4 mo & might reduce hospitalization risk from 0.5% to 0.3%, but if child already had #omicron then vaccine will be very effective against omicron!🤯 👉 nejm.org/doi/full/10.10…

Christopher Blyth (@chrisblyth74) 's Twitter Profile Photo

A key step to designing better pneumonia trials is designing better patient/ parent reported outcomes and PROMs. Great first paper by Dan Oakes, part of his MPH and a sign of great work to come WCVID telethonkids Daniel Oakes Charlie McLeod Barbara Nattabi err.ersjournals.com/content/32/167…

Eric Topol (@erictopol) 's Twitter Profile Photo

From a randomized trial, proof that the Novavax booster induces less acute side effects and more sustained levels of anti-spike IgG antibodies than mRNA shots Moderna Pfizer Inc. journalofinfection.com/article/S0163-… Right panel represents anti-spike IgG unadjusted fold reductions at

From a randomized trial, proof that the <a href="/Novavax/">Novavax</a> booster induces less acute side effects and more sustained levels of anti-spike IgG antibodies than mRNA shots <a href="/moderna_tx/">Moderna</a> <a href="/pfizer/">Pfizer Inc.</a> 
journalofinfection.com/article/S0163-…
Right panel represents anti-spike IgG unadjusted fold reductions at
Eric Topol (@erictopol) 's Twitter Profile Photo

"All vaccines were immunogenic with more rapid waning after mRNA vaccines" Graph below shows the anti-spike IgG response to ancestral strain and BA.5 variant for the 3 vaccines at multiple time points (GMC-geometric mean concentration)

"All vaccines were immunogenic with more rapid waning after mRNA vaccines"
Graph below shows the anti-spike IgG response to ancestral strain and BA.5 variant for the 3 vaccines at multiple time points (GMC-geometric mean concentration)