As the cold of December sets in, a reminder that another sublime summer will come to Boston in 2022... along with the 18th year of the Summer Institute in Biomedical Informatics #SIBMI for undergrad quants! Applications close January 31. bit.ly/sibmi-hms

The secret to staying calm as you prepare to give a good presentation is to remind yourself that you want to explain, not to impress.

Excited to share our latest work!! We uncover functional convergence of common+rare genetic risk factors for autism around 16p11.2, a region of longstanding mystery in neuropsych research 🧠 🧵 👇 (1/14) medrxiv.org/content/10.110…

Super pleased and grateful that my first first-author paper has been published! Thank you so much Luke O'Connor for your mentorship and support 😊

How does a genetic variant you observe only once or twice in 400k people affect a trait? Im excited to share my first PhD manuscript, co-led with Dan Weiner, MD PhD and supervised by Luke O'Connor, that develops a novel statistical approach to the problem of rare variant heritability

Exome-seq has catalyzed rare variant (RV) discovery. But unknown: RVs converge w/ common variants? As polygenic+pleiotropic? Improve population PRS+"missing heritability"? New method + answers to these q's, leveraging 400,000 UKB exomes: medrxiv.org/content/10.110… 🧵 (1/18)

So excited to share our work on the genetic architecture of rare coding variation, now published in nature nature.com/articles/s4158… This work was led by superstar co-first authors Dan Weiner, MD PhD and Ajay Nadig

Thrilled to announce: I'm starting a faculty position in the HMS Department of Biomedical Informatics DBMI at Harvard Med! The O'Connor Lab is crossing the river. 1/

I am looking for graduate students + postdocs to join the lab. Job posting to follow, but please reach out now if interested! (Find me at my Broad email.) /end

Join O'Connor lab!! Working with Luke has been an amazing experience!

📣We're hiring! Please RT and share. #postdoc position in statistical genetics at DBMI at Harvard Med. Salary above normal range.

Excited to share our work introducing a remarkably efficient approach to model linkage disequilibrium, now published in Nature Genetics nature.com/articles/s4158… This work was led by Pouria Salehi Nowbandegani and @WilderWohns