Out today The Journal of Immunology from first authors Bhesh Raj Sharma & Mohi Choudhury: ✅NLRP3-dependent cell death occurs in CASP1- & GSDMD-deficient cells with LPS + ATP, suggesting cell death pathway other than pyroptosis ✅Led us to identify NLRP3-PANoptosome in WT cells academic.oup.com/jimmunol/advan…

.The Journal of Immunology invites submissions of clinical and human immunology research papers for an upcoming special collection. Editors seek manuscripts presenting novel findings that derive from studying human subjects and/or human tissues. 👉 ow.ly/yTMO50Vxt7e

A new review from Dr. Kristin Hogquist at UMN Laboratory Medicine and Pathology focuses on interferon (IFN) production within the thymus and its effects on thymic APCs and developing thymocyte while also examining the importance of T-cell tolerance to IFN. Read it in The JI: ow.ly/QSJS50VEIEv.

Check out the program for the 12th meeting of the Canadian Oxidative Stress Consortium on June 11-13 at York University. Register today! Muscle Health YorkU KINE YorkUHealth YorkU - Science York University rame.fluid.events/2025COSC?pgid=…

Fantastic work by Inflammasome Lab showing in vivo the importance of regulating caspase-1 activity in inflammatory conditions! Caspase-1 self-terminates protease activity to enforce homeostasis and prevent inflammasome-driven diseases biorxiv.org/content/10.110…

Join us at the Canadian Society for Immunology Canadian Society for Immunology Symposium at #AAI2025 to hear cutting-edge insights on innate immune cell signaling in human disease. 🗓 Sunday, May 4 | 🕒 15:30–17:00 | 📍 Room 310 Don’t miss this stellar session! #IMMUNOLOGY2025

Hit the books with AAI Courses! Beginning at 11:00 in the AAI Booth Theater. Learn about everything AAI has to offer. #AAI2025 #IMMUNOLOGY2025™

Humbled to receive this recognition

#YorkU's Muscle Health Research Centre will be hosting the 16th annual Muscle Health Awareness Day (MHAD16) this Friday, May 9, bringing together researchers & students for a day of presentations and discussions on the topic of muscle health: tinyurl.com/msx9cfkr | #YUResearch

When is a change in mitochondrial bioenergetics reflective of 'mitochondrial dysfunction' vs 'intentional reprogramming'? Here we present traditional vs alternative interpretations of mitochondrial responses to muscle disuse. physoc.onlinelibrary.wiley.com/doi/10.1113/JP…

Important call from The Journal of Immunology—if your research involves human subjects or tissues, consider contributing.

Faculty position and research chair in Immunology - applications closing soon!

An editorial by Editor-in-Chief, Gail Bishop, Ph.D., discusses the negative pressures that early-career scientists face to publish their work in journals with high impact factors, both to achieve career metrics and to support grant applications. 🔗 ow.ly/HTKW50WbYX3

The June issue of The JI is online now! Find cutting-edge research, reviews, and commentaries on your favorite immunology topics. Read everything now: ow.ly/cVNx50WiiAe

Data suggest that the NLRP3 inflammasome engages an additional innate immune lytic cell death pathway, PANoptosis, for cell death beyond the early timepoints of innate immune responses, which may lead to new therapeutic targets. Learn more: ow.ly/ZkJy50WlNT1.

NEW open access paper from our by Shivam Gandhi and colleagues sciencedirect.com/science/articl… In early stage Duchenne muscular dystrophy, cardiac fibrosis (scar tissue) dominates in 2 of 4 chambers, and is completely prevented by a novel adiponectin receptor agonist (see image)

The July issue of The Journal of Immunology is online now! Including a special collection on human and #clinical immunology, this issue of The JI is full of exciting new research and reviews. Read the full issue online: ow.ly/bfEp50WuPGk.

This Pillars of Immunology article in the Human and Clinical Immunology special collection provides a commentary on 2 pivotal articles from 1993 that shaped the CD40-CD40L field of immunology and impacted understanding of human health. ow.ly/o78O50Wzsbt

Did you know that up to 30% of people with psoriasis eventually develop psoriatic arthritis? At the Krembil Foundation, we’re supporting research that digs deep into the immune system to uncover what drives Psoriatic Arthritis 🔍🧪

Howard Lutnick: "Let's turn the money that Biden would give away. Let's turn that to equity to the American people."