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Happy to share some new work on the epigenetic regulation of a human endogenous retrovirus (HERV) in cancer biorxiv.org/content/10.110… bioRxiv #CancerResearch . 🧵 (1/n)

🎯 We are so thrilled our new paper Nucleic Acids Res is out! IBUB-UB Biochemistry & Molecular Biomedicine UB Fantastic collab with the labs of Gordon Hager NIH & Franck Dequiedt Liège. Huge thanks to Greg Fettweiss, Kaustub Wagh, Diana Stavreva & Alba Jiménez, Andrea Alegre & teams 🎉🥳 academic.oup.com/nar/article/53…

NEW review article from Henikoff and Ahmad about emerging epigenomic mapping technologies to study chromatin regulation. Very comprehensive - great for beginners and experts alike! sciencedirect.com/science/articl…

Check out this 🧵from Eimear Lagan on our new Molecular Cell paper! We show how the H3K27M Oncohistone reprograms chromatin in DMG, creating a specific dependency on CBX4/PCGF4-containing forms of cPRC1 👇

Evaluating methods for the prediction of cell-type-specific enhancers in the mammalian cortex dlvr.it/TKvngd

Yale and Google trained a 27B parameter model, C2S-Scale, to unify single-cell transcriptomics and biological language for deep reasoning across genes and cells. It outperforms prior models in interpretation, QA, and perturbation prediction using reinforcement learning

Excited to share with all our latest work on the use of single cell tools in following IDH mutant AML patients during their treatment! Out today Cell Stem Cell !! An amazing collaboration with AK Eisfeld & Elli Papaemmanuil, PhD & Dan Landau !!! Driven by the impressive Maria Sirenko

SUM-seq out Nature Methods! 🚀 Ultra-high-throughput Multiplexed snATAC+RNA Used to: ⏳ link temporal macrophage GRNs to immune disease genetics 🩸 map T cell regulatory landscapes 🧬✂️ dissect TF function in hiPSC differentiation via CRISPRi/a screens doi.org/10.1038/s41592… 🧵

On the eve of #ASCO25, I am delighted to share results from the correlative analyses of the ANZUP phase II TheraP study, now published in Nature Medicine. Massive effort supported by dedicated co-investigators, coordinators, patients & families from 11 study sites across

Conservation of regulatory elements with highly diverged sequences across large evolutionary distances nature.com/articles/s4158… #journals #feedly

I’m very happy to share our latest ABRF - Genomics ResearchGroup study “The impact of PCR duplication on RNAseq data generated using NovaSeq 6000, NovaSeq X, AVITI, and G4 sequencers,” is now published in Genome Biology! genomebiology.biomedcentral.com/articles/10.11…

🚨New paper🚨 Excited to share our latest on nature today: The PIVOT PENALTY in research. nature.com/articles/s4158… More than five years in the making. Key finding: The impact of new research steeply declines the further a researcher moves from their previous work.

🧬 A great example of how CUT&RUN can untangle the relationships between distinct chromatin remodelers and transcription factors, which play critical roles in cancer. 📄 Read the full study: cell.com/molecular-cell…

Wait....what?! Another Study Featuring Droplet Paired-Tag!?! Single cell multiomics and 3D genome architecture reveal novel pathways of human heart failure bit.ly/3SlU8BU #Epigenetics #PairedTag #DropletPairedTag #SingleCell #HeartFailure epigenometech.com

NHS announced that it will start offering first liquid biopsy tests for diagnostics of lung and breast cancer; also planning expansion to pancreatic and gallbladder cancers england.nhs.uk/2025/05/nhs-fi…

🔬Applications for the EMBL Australia #PhD Course are now OPEN!🌟 Ready to kick-start your scientific career? Don't miss this opportunity to learn from Aus's best researchers! 📅 1-12 December, 2025 📍 South Australian immunoGENomics Cancer Institute, Adelaide ℹ️ Info & apply by 27 July: bit.ly/4kljhsO

Our new review is now online: everything you wanted to know (at least what is known in this nascent field) about promoter-enhancer locus dynamics but were afraid to ask. Great work Masha Nazarova! sciencedirect.com/science/articl…

🚨 New meeting this fall in Brussels! 🚨 Cutting-edge science, amazing colleagues, & a RARE career development workshop for trainees-covering pharma, consulting, writing, start-ups & more 🤩 #epigenetics2025 Registration is open!! EpiCypher, Inc. Fuks_Lab xcellsconferences.com/epigenetics2025

New in Cancer Discovery! 👏 Dr. Ruth Scherz-Shouval and colleagues unravel a pathway of CAF-mediated suppression of NK cells in #BreastCancer, opening possible avenues for new biomarkers and strategies for immune-based therapies. #TumorMicroenviromment 🔗 bit.ly/3ZdI9dx

Don't forget to register for #EREHD25! Our talk submission deadline has been extended to 12 JUNE 2025, so submit your abstract today to join our incredible speaker line up in Mexico this November 🇲🇽 🔗bit.ly/4kHWbw0