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Bread and butter - this is melanosis coli. The pigment is not melanin but is lipofuscin (cell debris ingested by macrophages). There was also a little hyperplastic polyp in the darkened mucosa (see endoscopic image).

Example of a ‘shoulder’ lesion in a high grade non invasive UC. Don’t overcall this as CIS. The edge of the papillary lesion creeps into flat urothelium. #bladderpath #gupath. Michelle_Hirsch (Donovan) speaks well on this subject!

60s F 6cm L1 epidural mass. FS picts… Craig Horbinski #pathx #pathtwitter #neuropath #cnsPath #neuropathology

Pretty brisk giant cell reaction in a sacrococcygeal #teratoma. #pathology #neuropath #PathTwitter

#GUpath prostate laser enucleation for BPH: worrisome luminal mucin? nah...just #beautyinb9 basal cell hyperplasia (can occasionally have mucin🚨+nucleoli)

Olfactory neuroblastoma: - Nests of small round blue cells with salt and pepper chromatin. - May have Homer-Wright rosettes, or arrangements of tumor cells around neuropil (blue box). See more annotated features at: pathlibrary.com/slidebox/?case…

CAR-T associated GI injury -Reduced plasma cells in lamina propria -Architectural distortion -Intraepithelial lymphocytosis -Mucin-depleted regenerative glands -Apoptotic debris -Severity of epithelial injury is disproportionate to the amount of lamina propria inflammation

Smears from a thyroid nodule revealing predominantly oncocytic cells an example of Bethesda Category III - atypia of undetermined significance #PathTwitter #MedTwitter #CytoPath #TuesTweet #CytoFellow

Challenging lesion on deck: Would you classify this as a keratinizing BCC or a basosquamous carcinoma? What histologic criteria tip the scale for you? Curious to hear your reasoning! #Dermpath #Pathology

🔬📷 Glomerulus with karyorrhexis, hyaline thrombi, and a cellular crescent in patient with class III lupus nephritis ~ #RenalPath #Pathology #Kidney #Nephrology

Textbook example of adenoid cystic carcinoma on #CytoPath. Remote history of submandibular gland resection.

💡We found the culprit causing acute gastric pain. 🌟Iron pill gastritis - Therapeutic iron pills/tablets induces & exacerbates erosive mucosal injury. - H & E shows areas of mucosal ulceration & extracellular crystalline iron particle deposition (Iron stain highlights it) #cwru

🔬 Pink, White and Blue 🔴⚪️🔵 ~ Adrenal cells at the intersection of cortex (right side) and medulla (left side) ~ #Histology #Pathology #GUpath #PathArt

Case of Blade Drag 🔬 Grossing blades can dislodge and drag tumor cells across the cut surface, creating artifacts that mimic invasion (👇) or falsely involve margins—especially in papillary tumors. #PathX #PathTwitter #breastpath

Histology of Breast at Various Ages Dr. Hoda. Histology Bootcamp-Breast #USCAP25 #PathX #pathology

Histopathologic changes in cryptorchid testis in 71 years old man demonstrating atrophic hyalinized seminiferous tubules with thick basement without spermatogenesis, interstitial fibrosis and Leydig cell hyperplasia. #pathology #GUPath #Cryptorchidism

#histopathology #bone #pathX #pathTwitter Gross and photomicrographs. Dx: Chondrosarcoma.

Happy Thursday 💖 #MalasseziaInfection No PAS needed to view this yeast family 😉 Spaghetti and meatballs #PityriasisVersicolor #dermatology #pathology

Retroperitoneal nodule. Can you nail this one? 🔨🔎 Poll below 🗳️👇 #PathPuzzle 🕵️‍♂️ Michigan Pathology #Pathology #PathX #PathTwitter

#pathclassics #BSTpath Chondrosarcoma If appendicular skeleton, atypical cartilagenous tumor ALT used Gross-lobular cartilagenous tumor 🔬 Hyaline cartilage with variable cellularity and atypia Infiltration seen as entrapped bony trabeculae, surrounded by cartilage on all sides