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Today, we have good news! Our lab was awarded an NSF grant to explore applications of AI to iPSC-derived cardiomyocyte maturation and organoids in collaboration with Dr. John Zhang at Dartmouth College. Looking forward to exploring this rapidly evolving space!

Today, we also have good news. The Alternatives Research and Development Foundation (ARDF) has funded our project to develop heart organoid-based models for studying human atrial fibrillation. Many thanks to ARDF for their support!

The Department of Biomedical Engineering at Michigan State University is looking for a new Chair, follow this link if you are interested: careers.msu.edu/en-us/job/5200…

Our mini-review on proton-sensing GPCRs & #oncogenesis is now out. Highlights critical link b/t aerobic glycolysis, first described by Otto Warburg, acidic tumor microenvironment & pro-oncogenic protection from #ferroptosis. #SpartansWill #TumorMicroenvironment #Ogremorphin

Human heart assembloids with autologous tissue-resident macrophages recreate physiological immuno-cardiac interactions biorxiv.org/cgi/content/sh… #biorxiv_bioeng

The MSU Pharmacology & Toxicology has just posted a tenure-system Associate/Full Professor position for a visionary MSU Drug Discovery Director to lead the next growth phase in MSU's drug discovery program. careers.msu.edu/en-us/job/5211…

We have a funded graduate student open position open to work on heart organoids and heart failure, if any current MSU students are interested, please send me an email or message here on Twitter. aguirrelab.org

Back in sunny San Diego!

🫀 Human cardiac organoids are complex, self-organizing 3D tissues that recapitulate human physiology. Check out these studies by Idan Refael Haim, Oren Caspi 🎗️, Aleksandra Kostina, Aitor Aguirre, & others in Circ: Heart Failure, Cell Proliferation, CDD press, & StemCellReports.

Check out most recent paper in collaboration with Conchi Estaras at Temple University: cell.com/cell-reports/f…