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Next up, we will discuss ERAs

Moving on to our prostacyclins:

Last but not least, selexipag!

Thanks for tuning into our PH Theme this month! See you next month for a review on burns!

#JournalWatch Despite being associated with diabetes control, weight loss, and ASCVD benefit, researchers found that increased GLP-1 levels were associated with increased 90-day mortality in critically ill patients with acute respiratory failure. journals.lww.com/ccejournal/ful…

🔥 This month we’re spotlighting burn care! Follow along for posts on injury mechanisms, surgical management, fluids, nutrition, and the pharmacist’s vital role. Thanks to Nicole Moreno Nicole Moreno , Daphne Boggs, and Jeremy Schmidt for the posts! #critPRN #PharmICU

#JournalWatch 🚨 New data on high-risk PE 🚨 Advanced recanalization with systemic thrombolysis, surgical thrombectomy, or catheter-directed treatments may significantly improve short-term survival vs. using VA-ECMO alone as a bridge to recovery link.springer.com/article/10.100…

Reminder - nominations and materials for the Critical Care PRN Awards are due June 20! Nominate your colleagues today! Details available here: communities.accp.com/discussion/rem…

#JournalWatch Is faster better? Controversy exists on how fast septic patients should receive 30ml/kg crystalloid? When compared with fluid within 1 hr, this study found that 30ml/kg crystalloid within 2-3h had lower mortality & intubation Critical Care Explorations

🚨 We’re now active on Instagram —joining our X and Facebook platforms! Follow for updates, journal club highlights, themed month posts & more.

Managing burns includes proper fluid resuscitation and nutrition support. Check out this infographic for key burn fluid formulas and nutrition tips. More insights on tackling hypermetabolism coming soon! #critPRN

#JournalWatch In the REMAP-CAP trial, a 7-day course of IV hydrocortisone in ICU patients with CAP did not significantly reduce 90-day mortalit. The trial arm was stopped early for futility. Modest reduction in shock duration observed link.springer.com/article/10.100…

🔥 Burn injuries trigger a profound hypermetabolic response—elevating energy needs, driving catabolism, and increasing demand for protein, calories, and micronutrients. Pharmacists play a key role in optimizing nutrition and recovery #critPRN

🫁 Inhalation injury can complicate burn care. Early intubation, pulmonary hygiene, and toxicology management (CO, HCN, MetHb) are key. Pharmacists assist with antidotes, sedation, and ventilation strategies. #critPRN

#JournalWatch #critPRN Go-live of premade alteplase kits for high-risk pulmonary embolism causing cardiac arrest shortens the time for meds to arrive to bedside for administration during cardiac arrest. academic.oup.com/ajhp/article/8…

#JournalWatch In patients presenting with AIS within 4.5 hours, those who received TNK+ mechanical thrombectomy vs mechanical thrombectomy alone, had higher rates of functional independence at 90 days nejm.org/doi/full/10.10…

Burn injuries drastically alter PK/PD, complicating med dosing & monitoring. Pharmacists are key to optimizing therapy, guiding TDM, & driving antimicrobial stewardship in this complex population. #critPRN

#JournalWatch #critPRN In this retrospective study, preemptive phenobarbital monotherapy was associated with decreased mortality, mechanical ventilation, and adjunctive sedative medication use compared with symptom triggered BZDs journals.sagepub.com/doi/10.1177/10…

Know a student, resident, or fellow interested in attending the ACCP Annual Meeting? The Crit Care PRN is sponsoring 2 student awards and 2 resident/fellow Travel Awards!. Application deadline is August 29, 2025: accp.com/stunet/award.a… and accp.com/membership/res…

#JournalWatch Admit to floor or ICU? This study published in Critical Care Explorations shows that machine learning (ML) models outperform traditional regression in predicting need for ventilation hospitalized patients with CAP. ML could enhance support clinical decision-making.