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exciting time for human pain neuroscience! with the NIH NINDSfunding PRECISION Human Pain Network including Rob Gereau Ted Price director of CAPS at UT Dallas and Weinqin Luo cell.com/neuron/fulltex…

The Handbook of Ephys is out!! doi.org/10.1142/14331 "How to Patch a Cell"- a quick-start guide for people who are fresh to whole-cell patching. "Multiple Whole-Cell Recordings"- goes into details of obtaining quality recordings of dual- to 4-cell patch. Enjoy!😃

biorxiv.org/content/10.110… Nice paper with thoughtful commentary

Huge thanks to ASRA Pain Medicine for this honor. The generous funds from this award will enable my lab to continue our pioneering work to develop #PROTACs as analgesics. And so, we are looking for a postdoctoral researcher to lead this in vivo TPD work and also help drive a new

I once quit a study section mid-review because a reviewer gave an exceptionally productive physician-scientist trainee (after 15 years of training) a non-fundable K08 score because of small deficiencies in their animal protocol. He said he was being 'fair.' I yelled at him and

News: Scientists design gene delivery systems for cells in the brain and spinal cord nih.gov/news-events/ne…

Introducing Bases, a new core plugin that lets you turn any set of notes into a powerful database. With Bases you can organize everything from projects to travel plans, reading lists, and more. Bases are now available in Obsidian 1.9.0 for early access users.

The MONARCH™ study has been published in Headache Journal. 🔗 sprpainrelief.com/press-releases… *The SPRINT PNS System is not intended to be placed in the region innervated by the cranial & facial nerves Results may vary. Important safety & risk info: bit.ly/2FU92NH

cell.com/consortium/bra… Impressive compendium of studies for neural access

For readers interested in ion channels as drug targets, this Review in the May issue focuses on voltage-gated sodium channels, such as Nav1.8, the target of the first new non-opioid analgesic to be approved in decades nature.com/articles/s4157… rdcu.be/enkq4

pubmed.ncbi.nlm.nih.gov/40408223/

investor.lilly.com/news-releases/…

pnas.org/doi/10.1073/pn… Important new work from Bruce Bean lab. Will this put a damper in the enthusiasm around NaV1.8 inhibitors (Suzetrigine, new SiteOne acquisition by Lilly). Does this explain the real but modest effects of VX-548? Much to consider.

We’re excited to announce positive results from our Phase 1 healthy volunteer trial of KT-621, our investigational, first-in-class, oral STAT6 degrader. The data surpassed our target product profile, exceeding our expectations. As the first reported clinical data for a

Truly honored to receive this award and so grateful for the generous support that will enable my team and me to rapidly advance our program on targeted protein degradation for pain control. Big thanks to Rita Allen Foundation and US Association for the Study of Pain the this unique opportunity. Also to

Worth checking out! Altered trigeminal afferents in patients with chronic eye pain.

This should be required reading by all graduate students and postdocs | A brief guide to statistical analysis of grouped data in preclinical research nature.com/articles/s4225…

Pain in the brain! check out the thread: bsky.app/profile/drdami… on the new preprint: osf.io/preprints/psya…