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Go check out our pre-print for imaging single RNA molecules with Mango II arrays. David Rueda MRC Laboratory of Medical Sciences (LMS) Imperial Medicine biorxiv.org/content/10.110…

Our new publication on single-molecule RNA imaging using fluorogenic Mango II arrays is now out in Nature Communications! nature.com/articles/s4146… A Mango II array plasmid will also be available from Addgene very soon. David Rueda MRC Laboratory of Medical Sciences (LMS) Imperial Medicine Simon Fraser University

For those who are interesting in using the new Mango II arrays, the plasmid we deposited to Addgene can be found here. addgene.org/127587/

Great to see the Unrau lab Simon Fraser University developing RNA Mango based #COVID19 testing kits. technologynetworks.com/tn/news/corona…. I am flattered people have cited our recent work, but the real praise here should go to Amir and Lena for their work. m.rnajournal.cshlp.org/content/early/…

A heroic solo effort by ⁦Miles Huseyin⁩ using single molecule approaches to dissect the dynamics and chromatin binding of PRC1 in live cells. biorxiv.org/content/10.110…

Fluorescent RNA aptamers are used as biosensors and tags for tracking transcripts. Trachman et al. and Adrian R. Ferré-D'Amaré @nih_nhlbi describe the X-ray crystal structure of fluorogenic RNA #aptamer Mango-IV, revealing a domain-swapped homodimer. bit.ly/2SMUeUy

Our Single Molecule Imaging Group have contributed to this Post-Transcriptional Gene Regulation edition with a protocol for imaging Mango II tagged RNAs in fixed and live cells. w/ David Rueda Dr. HARUKI IINO Adam Cawte Peter Unrau 📄link.springer.com/protocol/10.10…

If you're interested in imaging RNAs at single-molecule resolution using fluorogenic RNA aptamers, go check out our new methods paper in the new edition of MiMB's post-transcriptional gene regulation! link.springer.com/protocol/10.10… David Rueda Dr. HARUKI IINO Peter Unrau

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Check out our recent paper using new fluorgenic Mango RNAs to image small non-coding RNAs. #RNA MRC Laboratory of Medical Sciences (LMS) @ImperialCollege @Adam_Cawte rdcu.be/Ia18 lms.mrc.ac.uk/new-mangos-lig…