
Axel Grothey
@agrothey
Passionate about justice & tolerance, teaching & educating oncologists, caring for cancer patients, learning from mistakes. Opinions and statements are my own.
ID: 24327965
14-03-2009 04:24:19
5,5K Tweet
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Day 3 #ASCO2025 Before LBA1 + LBA5 break cover, it’s already been a 🙌 2 days for #GIonc !🧐 BREAKWATER: nejm.org/doi/full/10.10… DESTINY-Gastric04 nejm.org/doi/full/10.10… PANOVA-3 ascopubs.org/doi/10.1200/JC… LEAP-015: ascopubs.org/doi/10.1200/JC… ClaudinCarT : thelancet.com/journals/lance…






#ASCO25 #Plenary ASCO LBA1 - ATOMIC - mFOLFOX6 +\- atezoX1y in stage 3 dMMR colon cancer Alliance for Clinical Trials in Oncology n=712, 54% high-risk ➡️3yDFS 86.4% vs 76.7%, HR 0.50p<0.001 ➡️OS immature -2 deaths in combo arm 👏 Frank Sinicrope, MD Questions remain: 📌do we need FOLFOX? 📌 do we need 1



Great discussion by Myriam Chalabi on ATOMIC I still feel and like many of others, 2 cycles of neoadjuvant IO are enough, for all pts with stage 3 dMMR ca colon pts . We have learned this from melanoma , that neo adjuvant IO is way better than Adjuvant IO Sorry, ATOMIC






Organ preservation is definitely not controversial with this group of KOLs. Fantastic to have trailblazing surgeons like them pushing the 💉 (literally). Julio Garcia Aguilar Laura Fernandez Geerard Beets #ESMOGI25 #ESMOAmbassadors ESMO - Eur. Oncology
