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Happy to see our new Review out! Engineering, applications, and future perspectives of GPCR‐based genetically encoded fluorescent indicators for neuromodulators - Rohner - Journal of Neurochemistry - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/jn…

When brain cells are active, specialized cells supply the long nerve connections with energy – at lightning speed and on demand. If this communication is disabled in mice, the nerve fibers are severely damaged as the animals age. news.uzh.ch/en/articles/me… Institute of Pharmacology and Toxicology Saab, Aiman S.

In our new study, we used fluorescent Localization microscopy to generate Hemodynamic maps of the whole Pial & Calvarial vascular connectome. Here, we used Pia-Flow in stroke, other applications for this transcranial powerful microscopy? #Topology #Velocity #direction #diameter

Together with the lab of Niek van Til from the UMC Amsterdam we treated vanishing white matter mice by in vivo base editing. Congrats to Desiree and Ilma to their work! cell.com/molecular-ther…

We’re thrilled to announce our latest preprint is now available on bioRxiv. Dive into our astrocyte research here: biorxiv.org/content/10.110…

Fantastic! Congrats Mohamad Amki and Susanne Wegener 🥳

I enjoyed coauthoring this Trends in Neurosciences spotlight with Dr Jessica L. Fletcher showcasing interesting research from Saab, Aiman S. and others in the area of oligondendrocyte-axon interactions.

'Do oligodendrocytes regulate axonal glucose uptake and consumption?' 'Spotlight' commentary by Jessica Fletcher Dr Jessica L. Fletcher & Kaylene Young Young Glial Research Team cell.com/trends/neurosc… discussing Looser et al. 2024 Nature Neuroscience, @Aiman_Saab group nature.com/articles/s4159…

Happy to share our new paper published in PNASNews. growkudos.com/publications/1… via @growkudos I am incredibly grateful to all co-authors and contributors Bruno Weber Lab Daniel Razansky Susanne Wegener Institute of Pharmacology and Toxicology Unispital_USZ

Thrilled to have part of my PhD out Nature Neuroscience ✨ Oligodendrocytes (OL) contribute to Aβ plaque burden alongside excitatory neurons, the latter crucial for local & distal plaque seeding. Also shown is the non-linearity between Aβ levels and plaque load. nature.com/articles/s4159…

The Swiss National Science Foundation has approved Consolidator Grants for three projects by UZH researchers Aiman Saab, Timo Boppart and Enzo Nussio. 👏 Additionally, 14 early-career researchers at UZH benefit from the SNSF funding program Ambizione: news.uzh.ch/en/articles/ne…

Thank you Bruno Weber Lab for the kind words :) it's an honor to collaborate with such a great team!!

Thrilled to announce that my talented student Zainab Faik has won the Best Poster Award at the ICBEM 2024! Proud to witness their journey and success. Onwards and upwards! 🌟

Excited to share our latest study! Today in Nature Methods the Gerald Schwank and Krauthammer Lab report in Kim Fabiano Marquart et al. 'Effective genome editing with an enhanced ISDra2 TnpB system and deep learning-predicted ωRNAs' (1/6) nature.com/articles/s4159…

Phew!Just wrapped a great discussion with Violetta Gogoleva & @BecherLab on MPs in neuroinflammation Trends in Immunology and now we have the first functional evidence🚨of MdCs as key drivers of oxidative tissue damage (also first study from the Mundtlab led by Juan Villar-Vesga) Checkitout👇

My thoughts are with friends and family in Lebanon. Wishing peace for the country of my childhood.

You knock out #GLUT1 to impair astrocytic glucose uptake - only to find out that #astrocytes ramp up glycolysis and keep going. Metabolically resilient, and even neuroprotective. Our study in Nature Communications: nature.com/articles/s4146…