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@VirusPathways Do not stock up too much because new and improved non-isobaric stable isotope labels for plexDIA are coming up soon. We are determined to extend the framework to high-plexDIA and actively working on it.

Back by popular demand, we are holding our Biological Data Science Workshop virtually again, FOR FREE!! August 8-19. #datascience #biology #bioinformatics #AI #NSF #Drexel #RowanUniv #UChicago

Need to get some writing done? Come by our writing hours today!

Heard that someone told a group of undergrads that they shouldn’t cold email professors about research opportunities… I mean obviously get lots of opinions from lots of people, but you should ABSOLUTELY be cold emailing professors to ask about research opportunities.

A milestone for a young field: We organized a community effort to make initial recommendations for performing, benchmarking, and reporting single-cell proteomics experiments arxiv.org/abs/2207.10815 You can contribute to the recommendations at: single-cell.net/guidelines

I'm recruiting scientists with an eye for design to help build Nucleate into an iconic biotech education brand. Sound like you? DM or email me.

Spent the past few months at Convergent Research learning how to build unconventional organizations. Wrote a list of things grad school doesn't teach scientists: sabrinasingh.xyz/writing/notes-…

Most of these tips also apply to writing research papers, making scientific posters, or in general communicating your research - think about your audience and “know the product”!

Game-changing news!

Food for thought about dimensionality reduction

Genomics company Illumina just unveiled its fastest, most cost-efficient DNA sequencer yet. The machine will deliver a $200 human genome and will be able to generate 20,000 of them a year. wired.com/story/the-era-…

pSCoPE increases data completeness: ◼️ by 171% for challenging peptides => data completeness reaches 94 % for all proteins biorxiv.org/content/biorxi…

Great news for the DNA world! With the new instrument from Illumina, the sample throughput is more than doubled (7,500 to 20,000 genomes a year), while the cost per genome has also decreased (~$600 to $200). Will this enable increased prevalence of DNA sequencing in the clinic?

Flagship startup Cellarity has raised $121 million series C for its approach to screen drugs against whole cells, rather than individual proteins. The technique relies heavily on single cell RNA sequencing and machine learning. bostonglobe.com/2022/10/04/bus…

Which are your favorite single-cell RNA-seq datasets from PBMCs and why?

One of the many reasons I chose #R. True story. 🧵 #rstats #datascience

Learn from Aleksandra Petelski, Nikolai Slavov, and Harrison Specht of Northeastern U. how to prepare mammalian cells for single-cell proteomics analysis using commercially available reagents and tools. Watch on JoVE: hubs.ly/Q01yqbWx0 Aleksandra Petelski #MassSpec

Our SCoPE2 protocol was selected as JoVE Article of the Month: jove.com/v/63802/single… Congrats to Aleksandra Petelski and @harrisonspecht! linkedin.com/posts/jove_jov…

Cells are very fast and crowded places. A molecule of glucose flies through a cell at 250 mph. A protein tumbles 60 million times per minute. These numbers seem made up. How did we figure this stuff out?