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Here it is: Our mini-review on how gut microbes react to human-targeted drugs. We hope you enjoy reading it!

👶🦠Infant microbiomes have 5 different trajectories of development over the first 2 years of life, driven strongly by initial microbiome colonization and environmental exposures nature.com/articles/s4146…

Exciting job opening! 🔬 Join DSM-Firmenich as an Associate Scientist in microbiome research. Be part of a team shaping the future of health solutions through microbiome innovation! 🌿 Apply here: lnkd.in/ducRF2x7 #Microbiome #HealthTech #JobOpportunity

Harvard University is offering free online winter session courses No Payment is required, just register and start learning! 12 courses you shouldn't miss:

🎉 Super excited to announce that our study "Colibactin-driven colon cancer requires adhesin-mediated epithelial binding" is now published in Nature! Huge congratulations to first authors Maude Jans and Magdalena Kolata for their fantastic work! 1/6🧵🎉 nature.com/articles/s4158…

UMAP was introduced to biology with the claim that it 'preserves the global structure of the data' better than t-SNE. This matters arising article shows that the claimed global structure preservation can be entirely attributed to different choices of initialization. 1/2

It's official, PacBio has launched a new benchtop sequencer! Quick summary of the new Vega system: - instrument = $169k - consumables = $1100 per run - output = 60 Gbp, 24 hr run time This is the #HiFi sequencer #microbiology labs have been asking for. pacb.com/press_releases…

NOODAI: A webserver for network-oriented multi-omics data analysis and integration pipeline biorxiv.org/content/10.110…

Today we publish an (in my opinion) important paper in Nature Microbiology 🍾showing that gut physiology and environment are factors explaining substantial variations in human gut #microbiome composition and #metabolism🦠 Fantastic work Nicola Prochazkova et al. 👏 nature.com/articles/s4156…

If we look at thousands of proteins (i.e., signals) in the human blood, the protein most associated with chronic physical and mental illnesses is the **same protein** as the top marker for mitochondrial diseases: GDF15 When mitochondria cannot flux energy properly, the cell

Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. Djenet Bousbaine led the charge... nature 1/55

OUT NOW: Metagenomic immunoglobulin sequencing (MIg-seq) reveals IgA coating of microbial strains in the healthy human gut The Sonnenburg Lab Matt Olm Sean Spencer, MD, PhD nature.com/articles/s4156…

Ten species comprise half of the bacteriology literature, leaving most species unstudied bioRxiv Microbiology by Paul A Jensen biorxiv.org/content/10.110… B. subtilis is #6 😍, anyhow, the literature is biased to models Would publications on plants or animals be similarly biased?

We found that many bacterial species use exogenous peptidoglycan fragments - released by lysis of neighboring cells - as a general danger signal, triggering a danger response that protects bacteria against many dangers: biofilm formation. Details👇: nature.com/articles/s4156…

We release our protein chatGPT, Evola! 🌟 chat-protein.com Evola comes in two versions: 10B & 80B. The 80B model has a 1.3B Saprot encoder & a 70B LLaMA3 decoder. Trained on 546 protein question-text pairs with an 150 billion word tokens! 💡🔬 biorxiv.org/content/10.110…

OUT NOW - Gut microbiome signatures of vegan, vegetarian and omnivore diets and associated health outcomes across 21,561 individuals @fackelmeister Nicola Segata Segata Lab join_zoe Tim Spector MD (Prof) #microbiome #metagenomics #vegan nature.com/articles/s4156…

Visualizing gene structures in R? gggenes, an extension of ggplot2, simplifies the process of creating clear and informative gene diagrams, making genomic data easier to interpret and share. ✔️ Plot gene arrows to represent gene locations and orientations. ✔️ Visualize genomic

Lifestyle is a stronger predictor of aging and mortality than genetics. A new Nature study of ~500,000 people found: 🎯 17% of mortality variation was linked to lifestyle (exposome). 🧬 <2% of was explained by genetics. Here’s what you need to know 👇🧵 1/10

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In #Microbiome 🚨Introducing DRAMMA: a machine learning method for predicting new antimicrobial resistance genes without sequence similarity to known ARGs 📢Utilising features like protein properties, genomic content, and evolutionary patterns 👉doi.org/pbqf