Alex Lu (@alexijielu) 's Twitter Profile
Alex Lu

@alexijielu

Researcher at @MSFTResearch. I study how AI can learn biology through puzzle-solving. Deaf and queer (he/his)

ID: 1060625456695779328

linkhttp://alexluresearch.com calendar_today08-11-2018 20:09:49

1,1K Tweet

3,3K Followers

523 Following

Ava Amini (@avapamini) 's Twitter Profile Photo

excited to share & release ProtNote! 🧬📰 ProtNote enables protein-function annotation on new, unseen functions by fusing LLM embeddings of text descriptions w/ protein sequence embeddings 📎biorxiv.org/content/10.110… 🖥️ github.com/microsoft/prot… led by the incredible Samir Char

excited to share & release ProtNote! 🧬📰

ProtNote enables protein-function annotation on new, unseen functions by fusing LLM embeddings of text descriptions w/ protein sequence embeddings

📎biorxiv.org/content/10.110…
🖥️ github.com/microsoft/prot…

led by the incredible <a href="/Samir_char/">Samir Char</a>
Kevin K. Yang 楊凱筌 (@kevinkaichuang) 's Twitter Profile Photo

We made sequences generated by EvoDiff in the lab! - Unconditional generations express, fold, and exhibit expected secondary structure elements - We inpaint functional intrinsically-disordered regions and scaffold binders

We made sequences generated by EvoDiff in the lab!

- Unconditional generations express, fold, and exhibit expected secondary structure elements
- We inpaint functional intrinsically-disordered regions and scaffold binders
Tristan Naumann (@tristannaumann) 's Twitter Profile Photo

Interested in real-world evidence (RWE), LLMs, multimodal models, and research at the intersection of ML and Health? Join us next summer in advancing health at the speed of AI Microsoft Research Health Futures: jobs.careers.microsoft.com/global/en/job/…

Kayo Yin (@kayo_yin) 's Twitter Profile Photo

🚨New dataset + challenge #EMNLP2024🚨 We release ASL STEM Wiki: the first signing dataset of STEM articles! 📰 254 Wikipedia articles 📹 ~300 hours of ASL interpretations 👋 New task: automatic sign suggestion to make STEM education more accessible microsoft.com/en-us/research… 🧵

Kevin K. Yang 楊凱筌 (@kevinkaichuang) 's Twitter Profile Photo

You have 10 more days to apply for an internship with me, Ava Amini Alex Lu Lorin Crawford, or Kristen Severson! Make sure you include a research statement with your application. jobs.careers.microsoft.com/global/en/job/…

Alex Lu (@alexijielu) 's Twitter Profile Photo

At NeurIPS and interested in talking about BioML? Catch me at the Microsoft booth in the expo hall between 2:00-2:30p and 3:30-4:30p today!

Dan Goldstein (@dggoldst) 's Twitter Profile Photo

Microsoft's Computational Social Science group may have the opportunity to hire one researcher Senior: 0-3 yrs post PhD jobs.careers.microsoft.com/global/en/job/… Principal: 3+ yrs post PhD jobs.careers.microsoft.com/global/en/job/… Please note: our ability to hire this season is not certain

Kevin K. Yang 楊凱筌 (@kevinkaichuang) 's Twitter Profile Photo

We compared the calibration of various machine learning uncertainty estimation methods for protein engineering. No method excels across all scenarios, and uncertainty-based strategies for optimization often did not outperform methods without uncertainty.

We compared the calibration of various machine learning uncertainty estimation methods for protein engineering. 

No method excels across all scenarios, and uncertainty-based strategies for optimization often did not outperform methods without uncertainty.
Ava Amini (@avapamini) 's Twitter Profile Photo

How well do single-cell foundation models perform w/o finetuning? Our work Genome Biology shows that in zero-shot settings, scGPT and Geneformer often underperform traditional methods, raising questions about their utility for biological discovery. 📰 genomebiology.biomedcentral.com/articles/10.11…

How well do single-cell foundation models perform w/o finetuning?

Our work <a href="/GenomeBiology/">Genome Biology</a> shows that in zero-shot settings, scGPT and Geneformer often underperform traditional methods, raising questions about their utility for biological discovery.

📰 genomebiology.biomedcentral.com/articles/10.11…
Alex Lu (@alexijielu) 's Twitter Profile Photo

Read our preprint that demonstrates a growing bias in medical imaging datasets against pediatrics, and how it impacts downstream AI development! Props to our first author Stanley Hua, who among many other feats, filtered hundreds of datasets/papers to establish this trend.

Alex Lu (@alexijielu) 's Twitter Profile Photo

Was incredible to work with Arushi during her summer internship - check out her preprint showing that single cell representation learning methods for microscopy can be confounded by cells in the background of their inputs!

Alex Lu (@alexijielu) 's Twitter Profile Photo

Read our Microsoft Research blog post about how the lack of pediatric patient representation in public medical imaging datasets is limiting the benefits of medical AI for children: microsoft.com/en-us/research…