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We had a blast writing this mini-review on the recent discovery of the mito-NAD transporter in mammalian cells, & what it could mean for the broader field of NAD biology. Alex Bott Yeyun Ouyang Giulio Superti-Furga @KoryLab Tim Luongo Enrico Girardi Trends in Biochemical Sciences authors.elsevier.com/a/1ccL33S6GfF7…

Out online today. Congrats to our talented postdoc Viplendra Shakya for his work identifying a nuclear-based QC pathway for non-imported mitochondrial proteins we call mitoNUC. U of Utah Dept of Biochemistry University of Utah #mitochondria elifesciences.org/articles/61230

Our amazing postdoc @dr_nowinski is moving on to Metabolism and Nutritional Programming at VAI as an Assistant Professor this summer! We will miss you, don't forget about us when you're famous! HHMI U of Utah Dept of Biochemistry #RisingStar Women in Mitochondria

Welcome To Van Andel Institute (VAI) Sara @dr_nowinski! We are very excited to have you join Metabolism and Nutritional Programming at VAI. Great science to come indeed!

This week, we're showcasing two great talks from authors: 04.13 Ahmad Cluntun (Ahmad A. Cluntun) of University of Utah 04.15 Toshiya Nishimura of Stanford University jrnlclub.org/this-weeks

Ahmad Cluntun Ahmad A. Cluntun of the Rutter Lab Stavros George Drakos labs identifies the pyruvate-lactate axis as a critical node in cardiac health disrupted during hypertrophy. Cell Metabolism University of Utah HHMI #cardiac #heart #JRNLclub jrnlclub.org/research-films…

Congrats to Dr. Peng Wei 魏鹏 for successfully defending his PhD thesis titled "An Unexpected Metabolism Crosstalk: Non-canonical convergence of carbohydrate and glutamine metabolism is required in 3D environment" today! U of Utah Dept of Biochemistry HHMI #PhDone 🥂

In the midst of all of the debate on CNS papers & chalktalks, you may have missed that just like ye, we dropped a couple of preprints over the weekend! Tonight on #MitoMonday we briefly highlight one, and save the other for next week. #LateNightWithTheRutterLab #DONDA

Monday, Monday, #MitoMonday! Protein-metabolite interactions are the coolest thing since sliced bread and, as promised, tonight we will briefly highlight our recent pre-print describing our platform designed for their systematic discovery. Drizzy #CLB #LateNightWithTheRutterLab

We are currently recruiting a Research Scientist in Proteomics to join the dynamic and diverse research team at Van Andel Institute (VAI) in Grand Rapids. More details at the link below: jobs.silkroad.com/vai/VAICareerS…

Our latest paper just came out! Spearheaded by former grad student Peng Wei 魏鹏, we show that mitochondrial pyruvate can support lymphoma proliferation by fueling a non-canonical glutamine metabolism pathway. bit.ly/3SIG57s @RJDLab HHMI Science Advances U of Utah Dept of Biochemistry

Very happy to share our work on the function of MPC in regulating lymphoma proliferation. Thanks to everyone who contributed to this work, it couldn't have been done without your help!

A team led by Drs. Weiwei Dai and Jianliang Shen studied #livercancer growth, finding that #beta-catenin induced the expression of glutamine synthetase (GS), but genetic ablation of hepatic GS accelerated the onset of liver tumors. 📖: Journal of Clinical Investigation bit.ly/3N70iCB

Happy to see the final version of our paper published in eLife - the journal! Phenomenal work by @realjakewinter on the intersection of mitochondrial protein quality control and cell death!🎉🎈🎊🥳 bit.ly/3gt5bKe HHMI U of Utah Dept of Biochemistry

"The development and publishing of the MIDAS platform has been a long road. KevinHicks deserves the lion’s share of the credit for making it happen. We have had an amazing and large group of collaborators that have contributed in essential ways" -JR bit.ly/3JrSlaN 1/2

New paper on model system our team designed to study how metabolic stress affects the biology of pancreatic tumors: elifesciences.org/articles/81289. A thread. TLDR: We learned if you grow your cells with the nutrients they would see IRL, they will start behaving like they do IRL.

An exceptional day at an extraordinary conference! Gratitude to the Keystone Tumor Metabolism organizers for the opportunity to showcase my research. A special thank you to Eileen P. White, PhD and the Rutgers Cancer Institute for their unwavering support. Keystone Symposia

Recruiting a research tech to join the growing Hilbert Lab Boston College Biology Department ! We're looking for curious scientists to help us build a supportive research environment and tackle adventurous new projects investigating host-fungal interactions. Apply: tinyurl.com/ev8bx7au Please RT!

📢 New preprint alert! 🚨 We show that diet quality, not just quantity, is a key player in driving pancreatic cancer progression. 🔑 What you eat may matter for cancer risk—much more than we previously thought. #PancreaticCancer #CancerBiology #DietAndCancer