Alfonso De Stefano (@alfdestefano) 's Twitter Profile
Alfonso De Stefano

@alfdestefano

MD, PhD. GI Medical Oncologist - Abdominal Medical Oncology Unit - INT Fondazione G. Pascale - Napoli @istitutotumori

ID: 359498297

calendar_today21-08-2011 17:58:10

567 Tweet

258 Followers

396 Following

Alfonso De Stefano (@alfdestefano) 's Twitter Profile Photo

Medical.watch - See what physicians are saying about your brand on social media The weekly newsletter on CRC is now available for subscribers ⁦Medical.watch⁩ ⁦Kate Sears⁩ my.medical.watch

International Society of Liquid Biopsy (@isliquidbiopsy) 's Twitter Profile Photo

Liquid Biopsy Response Evaluation Criteria in Solid Tumors (LB-RECIST) 🔍 Key Highlights: ✅ctDNA dynamics can predict treatment response earlier than imaging. 📊 ✅Proposed LB-RECIST criteria aim to standardize ctDNA-based response assessment. 📝 ✅A step forward for

Liquid Biopsy Response Evaluation Criteria in Solid Tumors (LB-RECIST) 

🔍 Key Highlights:

✅ctDNA dynamics can predict treatment response earlier than imaging. 📊
✅Proposed LB-RECIST criteria aim to standardize ctDNA-based response assessment. 📝
✅A step forward for
Alfonso De Stefano (@alfdestefano) 's Twitter Profile Photo

Historic milestone 🎯🥇 for first-line #mCRC treatment of #BRAF V600E mut patients based on #BREAKWATER study FDA grants Accelerated Approval to Encorafenib Plus Cetuximab and Chemo for BRAF V600E+ Metastatic Colorectal Cancer OncoAlert #GIonc fda.gov/drugs/resource…

Alfonso De Stefano (@alfdestefano) 's Twitter Profile Photo

🙏🏻 Grateful to Medical.watch and Kate Sears to promote the results of IMPROVE trial on Journal of Clinical Oncology ascopubs.org/doi/pdf/10.120… in the weekly newsletter! To be always updated on the most recent news and trials, you can subscribe at my.medical.watch/signup

🙏🏻 Grateful to <a href="/MedicalwatchFTW/">Medical.watch</a> and <a href="/medicalwatchBC/">Kate Sears</a> to promote the results of IMPROVE trial on <a href="/JCO_ASCO/">Journal of Clinical Oncology</a> ascopubs.org/doi/pdf/10.120… in the weekly newsletter! To be always updated on the most recent news and trials, you can subscribe at my.medical.watch/signup
Alfonso De Stefano (@alfdestefano) 's Twitter Profile Photo

📢Very useful suggestions from Medical.watch Kate Sears directly forwarded to your📁📬email. You can subscribe to get a monthly update on phase 3 interventional clinical trials recruiting near you on your field of interest. Congrats and thanks for this project!

Alfonso De Stefano (@alfdestefano) 's Twitter Profile Photo

Interesting review on advances in targeting 🎯KRAS in #mCRC OncoAlert OncoDaily GI Development of KRAS Inhibitors and Their Role for Metastatic Colorectal Cancer by Dustin Deming on Journal of the @NCCN jnccn.org/view/journals/…

Alfonso De Stefano (@alfdestefano) 's Twitter Profile Photo

Thanks OncoDaily to share our results from #IMPROVE trial Continuous(C) vs Intermittent(I) ChT in #mCRC Journal of Clinical Oncology ascopubs.org/doi/pdf/10.120… ✅Endpoint met 👉mPFSot 11.2(C)vs17.5months(I) 👉NO detrimental effect on OS 👉DCR 94.2%(C)vs91%(I) 👉⬇️skin tox oncodaily.com/blog/panitumum…

OncoDaily GI (@oncodailygi) 's Twitter Profile Photo

Intermittent or Continuous FOLFIRI + Panitumumab RAS and BRAF Wild-Type Metastatic CRC oncodaily.com/url/225453 Dr Akhil Santhosh Alfonso De Stefano #Cancer #GIOnc #Crcsm #MedEd #MedX #MedNews #Health #Medicine #OncoDaily #Oncology

Myriam Chalabi (@myriamchalabi) 's Twitter Profile Photo

Long awaited practice-changing results from ph 3 CM8HW now out in The Lancet. Nivo/ipi sign better than nivo mono in dMMR mCRC Sara Lonardi Bristol Myers Squibb #GI25 thelancet.com/journals/lance…

NEJM (@nejm) 's Twitter Profile Photo

An analysis of published studies suggests that a longer duration of immune checkpoint inhibitor therapy is associated with a higher incidence of complete response among patients with mismatch repair–deficient cancers. Full correspondence: nej.md/3EXiEpe

An analysis of published studies suggests that a longer duration of immune checkpoint inhibitor therapy is associated with a higher incidence of complete response among patients with mismatch repair–deficient cancers. Full correspondence: nej.md/3EXiEpe
Alfonso De Stefano (@alfdestefano) 's Twitter Profile Photo

Many thanks to Digestive Cancers Europe to share our ongoing phase III #IMPROVE-2 trial, highlighting the possible advantages of #intermittent therapy with FOLFIRI-Panitumumab in RAS BRAF wild-type #mCRC patients digestivecancers.eu/improve-2-tria…

Arndt Vogel (@arndtvogel) 's Twitter Profile Photo

Intermittent or Continuous Panitumumab + FOLFIRI for 1st line RAS and BRAF WT mCRC Journal of Clinical Oncology doi.org/10.1200/JCO.24… 🔎IMPROVE Trial 👉ORR 68.1 vs 61.2%, 👉mPFS: 11.2 vs 17.5 mo 👉mOS: 36.3 vs 35.1 mo 🧐Intermittend Tx feasible, less tox ESMO - Eur. Oncology

Intermittent or Continuous Panitumumab + FOLFIRI for 1st line RAS and BRAF WT mCRC
<a href="/JCO_ASCO/">Journal of Clinical Oncology</a> 
doi.org/10.1200/JCO.24…
🔎IMPROVE Trial
👉ORR  68.1 vs 61.2%,
👉mPFS: 11.2 vs 17.5 mo
👉mOS: 36.3 vs 35.1 mo
🧐Intermittend Tx feasible, less tox
<a href="/myESMO/">ESMO - Eur. Oncology</a>
Michael Shusterman, MD (@guildsman) 's Twitter Profile Photo

14) IMPROVE Trial "Intermittent FOLFIRI plus PANITUMUMAB after the induction phase was feasible, and the primary end point was met with reduced toxicity while allowing patients more time off treatment." ascopubs.org/doi/full/10.12…

International Society of Liquid Biopsy (@isliquidbiopsy) 's Twitter Profile Photo

📢 Exciting update in the field of liquid biopsy! A new editorial highlights the essential role of the International Society of Liquid Biopsy (ISLB) in establishing quality framework for LB clinical implementation. 🧬🩸 This document underscores the importance of standardized

📢 Exciting update in the field of liquid biopsy! A new editorial highlights the essential role of the International Society of Liquid Biopsy (ISLB) in establishing quality framework for LB clinical implementation. 🧬🩸 

This document  underscores the importance of standardized
Christian Rolfo (@christianrolfo) 's Twitter Profile Photo

2025 ISLB Annual Congress, will take place in Orlando, Florida, November 1-3, 2025. This is an extraordinary gathering of scientists, clinicians, industry leaders, and innovators, all united by a shared passion for advancing liquid biopsy 2025.islb.info

2025 ISLB Annual Congress, will take place in Orlando, Florida, November 1-3, 2025. This is an extraordinary gathering of scientists, clinicians, industry leaders, and innovators, all united by a shared passion for advancing liquid biopsy 2025.islb.info