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Read our new study: nature.com/articles/s4225… Treatment of obese mice with small molecule inhibitors of mtDNA transcription (IMTs) leads to marked beneficial metabolic effects. The weight is normalized, the fat deposition in liver disappears and glucose homeostasis is normalized.

Congrats to our PhD student Lucía Luengo-Gutiérrez on the selection of her abstract for presentation at #DMMgenetics in Edinburgh! 🎓 #PhD MRC MBU MRC MitoCluster MRC National Mouse Genetics Network

Remember Nucleoid-phagy? PrudentLab Luis Carlos Tábara Rodríguez

Delighted to share the last study of the lab led by the fantastic postdoc Luis Carlos Tábara Rodríguez out in Cell !!! We show how MTFP1 controls mitochondrial fusion to regulate inner membrane quality control and maintain mtDNA levels. MRC MBU Cambridge University authors.elsevier.com/sd/article/S00…

We’re hiring! The Whitworth lab (Mitochondrial Neurodegeneration) is recruiting a postdoc to work on mechanisms of #calcium and #iron handling on #mitophagy in mouse or iNeuron models of neurodegeneration. jobs.cam.ac.uk/job/46870/ mrc-mbu.cam.ac.uk/research-group…

Thrilled to announce that our project has been published in Cell. In this work, we link mitochondrial dynamics to mitochondrial quality control and mtDNA maintenance by characterizing the molecular function of MTFP1. Please DM; happy to discuss! cell.com/cell/fulltext/…

📣New bioRxiv from mito911! Bishal Basak & Erika Holzbaur-Howland present a new stress response pathway regulating #mitophagy in #neurons through degradation of the autophagy negative regulators MTMR5/2 and Rubicon Aligning Science Across Parkinson’s michaeljfox.org biorxiv.org/content/10.110…

⚠️New issue of #mitophagy news 🪫🔋🗑️ Lots of papers, sorted by yours truly with the help of Bims: Biomed News biomed.news/bims-tofagi See below for highlights in the following categories: 1) Cellular & Molecular mechanisms 2) Pathophysiological relevance 3) Experimental tools

A small gift to celebrate the Postdoc Appreciation Week!! 😊 Thank you all for your great work and commitment to science! 🔬 The MBU Postdoc Society MRC MBU Postdocs MRC MBU (thank you Mariangela Dionysopoulou for your help 😉)

Please have a look at our recent review on mito-dynamics!

Inspiring science at the Postdoc Networking Day yesterday at AstraZeneca. Happy to have contributed to this wonderful event with the Cambridge Biomedical Campus and AstraZeneca. Huge thanks to Jonathan Lawson for organising this gathering. The MBU Postdoc Society

New study from us: science.org/doi/10.1126/sc… High mtDNA copy number promotes lung cancer growth in the mouse, whereas mtDNA depletion in tumor cells reduces tumor growth. This tumor-intrinsic role for mtDNA can be exploited for development of future lung cancer therapies.

Does a transmembrane sodium gradient control membrane potential in mam... sciencedirect.com/science/articl…

New paper out! #AMPK regulates #ULK1 to balance #mitophagy of functional vs dysfunctional mitochondria in Molecular Cell. Great work from authors, especially Marianna Longo Aniketh Bishnu and collaborators @Kei_Sakamoto Carol MacKintosh. See it here: tinyurl.com/AMPK-ULK

cell.com/molecular-cell…

We are excited to share our latest work on mechanisms that protect from mitochondrial dysfunction. Thank you to all collaborators and the 4th anonymous reviewer for supporting us. Matthias Mann Lab Nature Communications Florian Rosenberger nature.com/articles/s4146…

Paper alert. Insights on papers published in our special research topic on #mitochondria and #neurodegenerative_diseases, volume II Frontiers - Neuroscience. Great collaborating with you Alvaro Sanchez-Martinez Federica De Lazzari Gloria Brea Calvo Thanks to the reviewers too! frontiersin.org/journals/neuro…

🚨 Calling all researchers in neurodegenerative diseases! 🚨 Submit your manuscript & join EMP in shaping the future of biomedical research. sciencedirect.com/journal/experi… Elsevier Pharma #NeurodegenerativeDiseases #CallForPapers #BiomedicalResearch #Pharmacology #pathtwitter #Elsevier

Invitation to researchers specializing in Metabolism!📰 Submit your manuscript now and be part of EMP’s mission to advance biomedical research🤓 sciencedirect.com/journal/experi…… Elsevier Pharma #Metabolism #CallForPapers #BiomedicalResearch #Pharmacology #pathtwitter #Elsevier

🚨Attention Molecular Biology Researchers🚨 Submit your manuscript to EMP & contribute to advancing cutting-edge biomedical research! Learn more about our expanded scope here: sciencedirect.com/journal/experi… Elsevier Pharma #MolecularBiology #CallForPapers #BiomedicalResearch #Elsevier