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I’m at the point where I will rather quit than do American Board of Internal Medicine (ABIM) Longitudinal Knowledge Assessment (LKA) and try to keep ABIM certification active. It’s interfering with patient care and research for me. And I’m getting the myeloma questions wrong. Useless. Rafael Fonseca MD 🦔🇺🇸🏜🇲🇽 #MedTwitter

Janssen Submits Supplemental Biologics License Application to FDA Seeking Approval of CARVYKTI (Cilta-Cel) for Earlier Treatment (1-3 Prior Lines) of Patients with Relapsed/Refractory Myeloma #mmsm ⁦Multiple Myeloma RF⁩ ⁦The Leukemia & Lymphoma Society⁩ ⁦HealthTree Foundation⁩ prnewswire.com/news-releases/…

Beautiful Lugano

Federico et al - 10y FU H10 Take home: • omission INRT early fav led to signif ⬇️ PFS but no OS benefit • no diff in unfav disease (presum due to 6x chemo in non-RT arm) • benefit of BEACOPP escalation no longer statistically evident • no ⬆️ late tox RT or BEACOPP #17ICML

The phase 2 CAPTIVATE study has longer follow-up plus a considerably bigger I+V cohort than GLOW. 👇 This is from 4-year Captivate data on I+V (Ghia et al ICML 2023). Clear correlation of EoT-MRD with PFS also for Ibrutinib+Venetoclax in my view….

But Where is My Doctor? The Increasing and Relentless Fragmentation of Oncology Care Journal of Clinical Oncology ascopubs.org/doi/10.1200/JC…

ZUMA-7 trial: Patients with relapsed or refractory large B-cell lymphoma who received axi-cel (CD19-specific CAR T cells) had a 27.4% lower risk of death than patients who received standard therapy. Read the full study: nej.md/3qrRC23

Hmmm….

Masterpiece ! Vivre Avec Une NMP Karin Tourmente

Fantastic news for patients with DLBCL.

Cost-effectiveness of chimeric antigen receptor T-cell therapy in adul... sciencedirect.com/science/articl… #CART #bmtsm #CARTcell #immunotherapy #tcellrx #ICAN #CRS #CARTcells #CellTherapy #Gene #Genetherapy ASTCT Chimeric Antigen Receptor T-Cell (CAR-T) & Gene Rx #kite

With 35 wonderful colleagues from ⁦OxfordOncology⁩ ⁦NHLDS, Lacor ⁦Muhimbili University⁩ ⁦Muhimbili National Hospital⁩, KCMC, Bugando to bring liquid biopsy testing for Burkitts lymphoma to children in East Africa. Huge effort!So proud of the team!

How often can you say you had 3 generations of Nobel-winning women together in row 3? ✨ Women Deliver, can we count this as an unofficial pre-conference? 😉#WD2023

Chairman Imran Khan's message to the people of Pakistan shared through his family on the 10th of October: “When I was illegally incarcerated in Attock Jail, the first few days were particularly challenging. I wasn’t provided a bed and had to sleep on the floor and had insects

R-miniCHOP versus R-CHOP in elderly patients with diffuse large B-cell lymphoma ||American Journal of Hematology | Blood Research Journal | Wiley Online Library onlinelibrary.wiley.com/doi/full/10.10… #lymsm

This came out of the blue and seems on initial reading to be overblown. FDA opens review of CAR-T safety after identifying 19 cases of post-treatment blood cancer - endpts.com/fda-opens-revi…

FDA alters warning label for Carvykti CAR-T, although link to secondary cancers is unclear. #mmsm statnews.com/2023/12/22/mye… via STAT

I just wrote my first note on Substack substack.com/profile/225781…