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Extremely honoured to be awarded the Cancer Research UK Career Development Fellowship to study the impact of ER-phagy on cancer progression. I will be hiring postdocs and recruiting students soon at the MRC PPU. Please stay tuned! #autophagy #CancerResearch #erphagy #crispr Science and Innovation at Cancer Research UK

We talk to three new group leaders focusing on different aspects of quality control about their research and the process of setting up their labs: Chantell Evans @channyskye @evanslab, Jin Rui (Amos) Liang amosliang MRC PPU, and Cristina Mayor-Ruiz… dlvr.it/SP8Xzb

Check out our latest review summarizing various techniques & contributions of CRISPR-based screens on autophagy discoveries! We also discuss recent screening tech dev that can improve our understanding of autophagy in various contexts! #autophagy #CRISPR Jacob Corn

I'm in Dundee at last! I'm also interviewing postdocs to explore the roles of ERphagy. ppu.mrc.ac.uk/careers/recrui… Deadline approaching soon!

This #preprint finds a cryptic LIR used to coordinate #LC3 lipidation for #autophagy and spans all kinds of fun techniques. It's also just one of many super collaborations between Bode Group and my group. Much more to come! Jakob Farnung amosliang @matthias_muhar

Excited to reveal an essential function for protein degradation and quality control in development: shaping network dynamics to control gene expression and cell identity! Many implications for #TPD. A little thread. biorxiv.org/content/10.110…

#FanconiAnemia causes devastating bone marrow failure. But #CRISPR HDR editing doesn't work in cells from these patients. In collaboration w/ Paula Río & funding @EJPRareDiseases we develop a #BaseEditing approach for bone marrow cells from FA patients. nature.com/articles/s4146…

I'm SO EXCITED to share our new pre-print! 🥳 You finally got your RNA-seq data. You open RStudio, stare at the screen for 5 mins...And realize you don't even remember how to import a table. How will you analyze your data?!😱We're here to help! A 🧵👇(1/9) biorxiv.org/content/10.110…

Postdoctoral Research Fellow position available in Liang lab: ppu.mrc.ac.uk/careers/recrui… #Autophagy #ERphagy #CRUK #CRISPR #cancerbiology #cellbiology amosliang

Pleased to see our new study on #Parkin activation - thanks to Michael Stevens and Odetta MRC PPU and great collaboration with Jean-Francois Trempe, Ted Fon The Neuro and Wolf Springer Mayo Clinic #teamscience

Hey everyone! We are the DundeeTrackers (4 PI's from UoD Life Sciences) and we are taking part in the Edinburgh Marathon Relay Race to raise money for Cancer Research UK Cancer Research UK in Scotland this Sunday! There is still time to make a small donation if you can! justgiving.com/fundraising/th…

Cells degrade unfolded proteins. But do they also check for chemical damage? We found that a C-terminal amide is completely sufficient for degradation by an SCF/FBXO31 ligase complex! With Bode Group @matthias_muhar Jakob Farnung. biorxiv.org/content/10.110… 🧵

Check out this exciting work coming out of Jacob Corn & Bode Group! Well done @matthias_muhar & Jakob Farnung!

Celebrating a successful MRC PPU quinquennial review 🥂

The second joint Christmas dinner between the Liang and Swatek labs. Both of our labs have come a long way since the first year! Grateful for everyone that takes a leap of faith in joining our labs.

Very interesting discovery and a super neat reporter system to study peroxisome import! Congrats @brookemeghan & richardson_lab

SAVE THE DATE!!

Registration for the joint Autophagy UK & Proteostasis UK meeting is now open. Going to be a great meeting and we look forward to welcoming you to Dundee!