🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

New bioRxiv from our lab by Qian Shao on a covalent 14-3-3 molecular glue with the transcription factors YAP and TAZ and using this glue as a 14-3-3 recruiter to sequester nuclear neo-substrates into the cytosol! Thanks to #AppleTreePartners & @themarkfdn

👇Great choice!

Our lab at Huntsman Cancer Institute University of Utah is hiring a junior-level tech! Come work on fascinating questions in signaling, development, and cancer with a dynamic and collaborative team. Great opportunity for future grad or med school applicants. Please RT! utah.peopleadmin.com/postings/155537

Excited to see this new pre-print out! Gets at the role of ubiquitin condensates as platforms for assembly of autophagy machinery. Fun collaboration w @jenscs83 David Broadbent Colten McEwan, PhD #autophagy

Alana L. Welm, recipient of the 2023 AACR Outstanding Investigator Award for Breast Cancer Research, delivered her award lecture this afternoon during #SABCS23. @AlanaWelm @UTHealthSAMDA AACR

We’re looking to hire some undergraduates! 👇

If you’re coming to #DiscoverBMB, please join Castaneda Lab and us for an interest group on phase separation/condensates and cell signaling. Fantastic speaker lineup! 👇

Thanks to the visionary developers of @UtahCityUtah—Woodbury Corporation & Flagship Companies, along with @VineyardCity, we've received an incredible $20 million land donation. This will pave the way for a state-of-the-art HCI campus in Utah County. bit.ly/3vTfPkQ

I would like to thank ASBMB for this travel award to attend #DiscoverBMB 2024. I’m so excited to present part of my research project and see what other “cool science” is happening out there! #CancerResearch #HCI #AndersenLab #LatinasInScience #MexicanasInScience 🇲🇽🇱🇷

We are immensely grateful to Utah City for their generous land donation and for the exciting vision they have created. This new campus in Utah County promises expanded world-class care, breathtaking views, and reduced travel burden for patients: bit.ly/3vTfPkQ

Congratulations Alex! Another bit of the ATG9A puzzle Exploring the ATG9A interactome uncovers interaction with VPS13A journals.biologists.com/jcs/article/do…

Nature review article: A break in mitochondrial endosymbiosis as a basis for inflammatory diseases go.nature.com/3OAPC0C

Happy to see it in print! 👇Intrigued by disease mutations clustering around PTMs #kinase #cellsignaling #proteomics Congrats Eranga Roshan

Check out our new review article on ciliary signaling, now online at Nature Reviews Molecular Cell Biology - a great collaboration with Keren Hilgendorf and Reiter Lab!

Our paper on functional discovery of protein degradation and stabilization effectors with proteome-scale induced proximity screens is out in its final version! 1/ nature.com/articles/s4158… rdcu.be/dBUju

Targeted protein degradation/ stabilization are of therapeutic value, but only few E3 ligases and deubiquitinases have been of use for this purpose. Work ⁦⁦nature⁩ adds to this repertoire, providing a catalogue of effectors of protein stability. nature.com/articles/s4158…

Our ASBMB #DiscoverBMB session on cell signaling and protein phase separation starts at 2:45. Come for great talks and panel discussion!

Congrats to Tania Lopez, MSc 👇

Flashing the U with Judith Simcox PhD at #DiscoverBMB and flashing back to our shared time at U of Utah Dept of Biochemistry

🚨Out in Molecular Cell, “Molecular Determinants and Signaling Effects of PKA RIα Phase Separation” by Julia C. Hardy establishes that a non-canonical, active PKA R:C complex in RIα condensates sequesters PKA activity from the cytosol. tinyurl.com/MolDetRIa