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New preprint: A modified GPT architecture to model the course of health and more than 1000 diseases throughout life. Delphi-2M estimates the risk of almost any disease, samples health trajectories and offers insights into the temporal dependencies of co-morbidities. More below.

I am recruiting a quantitative/computational postdoc to my group at UCLA. This is a great opportunity to work on foundational theory, methods, and software in statistical genetics. Link to apply below. Please repost!

"Do peer-review panels select the best science proposals?" x-axis: NIH grant percentile scores y-axis: how many citations and papers those grants produce (normalized)

Proud of my (recently graduate) student Teng Hiang for her first PhD paper, out today in AJHG . She studied recessive effects across diseases in ~44k British South Asians from the @GenesHealth and found 185 independent hits, >40% of which are novel cell.com/ajhg/pdfExtend….

ANGPTL4 inhibition with MAR001 can safely and effectively reduce circulating triglycerides and remnant cholesterol Congrats Marea Therapeutics Beryl Cummings 🙌 thelancet.com/journals/lance…

We are looking for a post-doc/research fellow working on non-bullshit, reality-centered AI. Meaning: unique nationwide EHR and -omics with the possibility to recontact people and prospectively test multimodal AI approaches. jobs.helsinki.fi/job/Helsinki-R… FIMM HelsinkiUni FinnGen

Very very interesting!

I didn't have much hope that we'd find genetic determinants of long-COVID, but after years of work, Vilma Lammi, Tomoko Nakanishi, Hugo Zeberg and Hanna M Ollila made it happen! nature.com/articles/s4158…

Exciting to share our paper on genetics of #longCOVID with Vilma Lammi, Tomoko Nakanishi, Hugo Zeberg and many others! nature.com/articles/s4158…  HiLIFE_Helsinki University of Helsinki Mass General Brigham Research

We are presenting tomorrow in Milan at #ESHG #ESHG2025 session C02 GWAS: Bigger, faster, stronger (10:30 am Auditorium) 💁‍♀️ Come and catch me if you can 🤫

Did you know that some genetic males have plasma proteomes similar to those of genetic females and vice versa? What are the consequences of this? Come discuss with me at our poster number P18.021.D on Monday 26.5. at 4pm-5pm at #ESHG2025

🚨 Great opportunity at FIMM, University of Helsinki! We're hiring early-stage group leaders in molecular medicine. Feel free to reach out if you're interested! 🔗 jobs.helsinki.fi/job/Helsinki-F… #academicjobs #sciencejobs #academiccareer #groupleader #research

Matteo Ferro, a doctoral candidate in my team has a new blog on health data science where he is collecting the most interesting papers, each month. Check it out! healthdatascience.substack.com

We have 2-3 group leader positions opening up FIMM HelsinkiUni !! We are looking for outstanding candidates in human genetics and precision medicine. This time we have a particular focus on population health data science. E.g. AI for EHR/health data jobs.helsinki.fi/job/Helsinki-F…

Good morning all. After yesterday's excitement about the CHALLENGE exercise trial, here is my critical appraisal on Sensible Medicine #ASCO25

Today, we are thrilled to announce that Verve Therapeutics has entered into a definitive agreement to be acquired by Eli Lilly and Company From 2018 to 2025, Verve moved a new concept (a one-dose future for the treatment of atherosclerotic cardiovascular disease) and a new medical technology (in