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Great overview of early life immune-microbe interactions Nature Rev Immunol by Katherine Donald & Brett Finlay So much to discover in this field! nature.com/articles/s4157…

Do you want to learn how to collect ≈900 blood-derived samples in one day? Check this paper from Stefan Reitzner, Petter Brodin and Jaromir Mikes 🇸🇰|🇸🇪4🇺🇦 Scalable in-vitro immunostimulation of human blood for in-depth profiling of acute immune response effects biorxiv.org/content/10.110…

📢 day 2 Petter Brodin ✅⬆️ HMO utilizing microbes 🔑 for gut health ✅1st weeks to months impact metabolites/microbiota/immunity long term ✅dx probability highest at birth and exposure post-birth ⬇️ risk - switch in hematopoietic system? #HavingIMPACTT2023 IMPACTT Microbiome

📢 Exciting News! Our latest paper is now out in Nature Biotech 🌱🧬 We developed GEARS---an AI method to predict cellular responses to genetic perturbation. 🧪🔬 🔗 Link to the paper: nature.com/articles/s4158… 🧬 Unraveling genetic interactions in cancer, regenerative medicine,

Researchers at Gladstone and UC San Francisco used a new method to screen 10,000 combinations of gene edits in immune cells engineered to fight cancer. Cell @MarsonLab Ansu Satpathy Blaeschke Lab Stanford Medicine bit.ly/3EHQ5ZP

How does optimal transport allow us to study dynamical systems? How does it connect to control theory, flow matching, & diffusion models? How is it advancing molecular biology research? Find the answers in our tutorial! Recording, slides, & script under bunne.ch/ot_tutorial/.

CONGRATS to my brilliant mentee Alex Doan for receiving a Society for Immunotherapy of Cancer Young Investigator Award! He'll be giving a short talk on memory reprogramming in CAR T cells at the annual meeting in November. Can't wait!

Beyond excited to present my research on memory reprogramming of CAR T cells at Society for Immunotherapy of Cancer 2023! Thank you to Evan Weber, @MackallLab, @molecular_elena, Kat Mueller, PhD, Andy Chen, and many others for collaboration, mentorship, and contributions to this work :)

A very thoughtful analysis on CAR-T bottlenecks in solid tumors nature.com/articles/s4157…

Still buzzing from Alex Doan and Kat Mueller, PhD presentations at #SITC2023. Couldn’t be prouder of these rockstar trainees 💪🏻💪🏻 See you next year Society for Immunotherapy of Cancer!

Out today in nature, we describe HHV-6 reactivation in T cells, including therapeutic CAR T cells. I’m so grateful to have worked with an all-star team during my time in the Ansu Satpathy lab that led to these findings. nature.com/articles/s4158… 1/n

Interested in LLMs for genomic research but don't know where to start? looking for a review/survey to get started in this field? 👇👇😀 I am very excited to share that our review paper titled "To Transformers and Beyond: Large Language Models for the Genome" is now available as

How to get lucky (without being rich): Thought experiment: If you had to double your luck in 6 months, what would you do? 10 ideas: 1. Luck Razor - If given 2 options, pick the one that has the most luck potential. E.g. Cocktail party vs watching Netflix. Which one has the

Our research introduces a system that enables you to generate 3D environments from text prompts and train embodied AI agents within them! Website: yueyang1996.github.io/holodeck/ Code: github.com/allenai/Holode… How did we leverage Objaverse assets to create interactive 3D environments? 👇

Excited to share my paper Nature Communications on the Taxol biosynthesis Sattely_lab sattelylab.bsky.social with some help from the Keasling Lab 🏳️‍🌈🏳️‍⚧️ 🥳 🎉 Really happy to have contributed to the studies of this amazing molecule 😊 nature.com/articles/s4146… (1/2)

Excited to share our work with Andy Chen, Katalin Danielne Sandor, Ansu Satpathy, and others on how inflammation-induced 3D genome conformation can integrate distinct inflammatory signals, and provide transcriptional memory in macrophages. biorxiv.org/content/10.110…

Memory genes are enriched in CAR T cells that persist and control tumors in patients. But which transcription factors drive beneficial memory programs? We answer this in our lab’s first paper in nature led by Alex Doan Kat Mueller, PhD Andy Chen. 1/ nature.com/articles/s4158…

I'm wildly proud to share our FIRST Weber Lab paper, out today in nature! I want to share a story about how this whirlwind of a project came together. A 🧵 on teamwork, open science, and how far we can go when we intentionally build a culture of trust in research. 1/

Happy to share our new work describing DESynR genes! The evolution of new human protein-coding genes relies on repurposing protein domains from ancestral genes, rather than de novo sequence creation. New genes evolved from old parts, and while we have methods that enable