🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Study led by Yi Fan Yi Fan and his talented team describes why CART cells for brain tumors might be effectively combined w FLASH radiation, a 🤯 new modality that could change how cancer is treated w RT. Thanks The Mark Foundation for Cancer Research for supporting this innovative work Penn Medicine!!

This study sounds very neat. Congrats!

In response to headline "Elon Musk and His Grok 3 AI Model Is Apparently Advanced Beyond Measure", I used Grok 3 to ask "If you were president of the US would you massively cut NIH funding" and "what about cutting NIH indirect costs". Here's answer from their AI reasoning model.

NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report forbes.com/sites/michaelt…

Please see our discovery of first-in-class BRISC deubiquitylating enzyme inhibitors rdcu.be/edRwF. A great journey with Elton Zeqiraj, Francesca Chandler, Joe Salvino. High-throughput screens, cryo-EM structure and ontarget activity to reduce inflammatory signals.

Live now: youtube.com/live/JofqSdWmh…

📢The Mark Foundation is hiring! 📢 Join us as a Scientific Director or Grants & Data Operations Coordinator and help us accelerate cancer research. #ScienceJobs #NonprofitJobs Learn more: themarkfoundation.org/careers/

🚨Today in Cell, we show that RNA splicing factor mutations in myeloid cancers generate splicing-derived public neoantigens targetable by #TCR tx. Amazing collaboration co-led by Abdel-Wahab Lab, Robert K. Bradley, and Klebanoff_Lab. #Tcellpower cell.com/cell/fulltext/…

We’re proud to see several members of our community named to National Academy of Sciences! Congratulations to ASPIRE Awardee Ali Shilatifard, Mark Foundation Center for Lineage Plasticity PI Corey Abate-Shen, and Scientific Advisory Committee member E. John Wherry! 🎉 themarkfoundation.org/blog/three-mar…

”If I get an award, I have an opportunity to thank people. I also thank the people who tried to make my life miserable because they made me work harder and become more resilient.” Next week, our podcast returns with conversations featuring our 2024 laureates. In the meantime,

Very neat work showing how chronic inflammation could alter the immune contexture of the tumor (eg T cell function) by impacting the tumor draining lymph nodes. A lot of implications! Congrats Santosh Vardhana and team.

Looking fwd, I am honored for this privilege of returning to MSK, working w immense talent to advance their mission of ending cancer. Looking back, I am indebted to Penn, all my colleagues, and to the organizations supporting the research of all who tirelessly share this mission.

Yet more brilliance from Chrysothemis Brown - its been a joy to have a front-row seat watching her group essentially rewrite the textbook on early life immunity. Kudos to one of the best scientists and human beings that I am fortuate to know! science.org/doi/10.1126/sc…

Please join us in celebrating the 2025 Pershing Square Sohn Cancer Prize winners! This year’s six scientists have been selected for their bold ideas and potential to transform cancer research. The winners are: pershingsquarephilanthropies.org/news/the-persh…

Congrats Chrysothemis Brown and team on this remarkable work! Some much welcomed good news. It’s exciting imagining the far-reaching significance to these findings — the power and consequence of “basic research” to understand how things work.

🙌🎉🍾Celebrating Fei and his recently accepted paper in Nature Cancer! Grateful to all of our collaborators, co-authors, and excellent peer reviewers Nathan Singh, #SaarGill, and Joshua Brody, MD. Stay tuned for the final manuscript! Memorial Sloan Kettering Cancer Center #Tcellpower #NKcellpower

Powerful piece on the dominance of NIH-funded science and its role in drug discovery. Cutting the NIH budget puts all the U.S. has built at risk. We urge Robert F. Kennedy Jr. | Commentary only & Jay Bhattacharya, MD, PhD to champion U.S. science and defend NIH funding statnews.com/2025/06/06/us-… via STAT

We previously showed that IFNg is required for CAR-T efficacy in solid tumors, but is it always good? Here, we show that IFNg limits CD28 CAR-T cells and that protection from this signal drives greater antitumor activity and durability. Enjoy! science.org/doi/10.1126/sc…

When the hardest cancers go unsolved, Anusha Kalbasi, MD (Stanford Medicine), gets to work. The PICI Investigator is a recipient of the 2025 CRI Lloyd J. Old STAR Award from Cancer Research Institute—recognizing investigators who take on cancer’s toughest questions. Dr. Kalbasi’s lab is reshaping

"But I am blown away by how much we have learned about Alzheimer’s over the last couple of years."—Bill Gates statnews.com/2025/06/17/bil… "This is the moment to spend more money on research, not less." Agree 💯 erictopol.substack.com/p/predicting-a… erictopol.substack.com/p/the-breakthr…