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Rethinking excitation/inhibition balance in the human brain — a Comment article by Roi Cohen Kadosh nature.com/articles/s4158…

We’re excited to share our latest publication in Nature Medicine, where we conducted the largest plasma proteomics study to date across three major neurodegenerative diseases: #AD, #PD, and #FTD. 📖 Read the paper: nature.com/articles/s4159… Global Neurodegeneration Proteomics Consortium WashU Medicine Knight ADRC

Can AI reveal the risk and co-pathology of multiple neurodegenerative diseases from just a single blood sample? We explored the AI-based diagnostic power on a massive sample (N=17,170) and high-rank plasma proteomics data. medrxiv.org/content/10.110… #MedSky #neuroskyence #neurosky

‼️New preprint‼️ Super excited to share this work by the incredible Lijun AN | 安丽军. We explore the potential of plasma proteomics and AI for neurodegenerative disease (AD, PD, ALS, FTD,CVD) diagnosis in a massive dataset (N>17,000). Paper link and walkthrough in Lijun's 🧵 below!

1/11 Excited to share our @Naturestudy led by Leon Ooi Csaba Orban Shaoshi Zhang doi.org/10.1038/s41586… It is well-known that AI performance scales with logarithm of sample size (Kaplan, McCandlish 2020), but in many domains, sample size can be # participants or # measurements...

Check out lab's latest preprint for MRI super resolution!!!

Out now in Nature Biomedical Engineering: We explore how rare high-effect gene-coding variants (#CNVs) shape brain architecture and influence cognitive and socio-behavioral traits in adolescents (#ABCD). nature.com/articles/s4155…

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CTAD taskforce: genetic therapies in Alzheimer’s disease. D. Jakabek et al. nature.com/articles/s4358… #AlzheimersDisease #GeneticTherapy #ClinicalTrials #CTAD #Neurogenetics #RNAtherapeutics #PrecisionMedicine #NeuroscienceResearch