🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

📢Have questions on #COVID19 vaccine, treatment & mutation? 👉🏻Send us your questions with #askCUexperts by 14 June! Our experts in microbiology and pharmacy will be here to answer. #HKTwitterGetsVaxxed

We're excited to hear from David Chen, PhD, of City of Hope as he introduces sc-Tiling, a #CRISPR-based method for #genefunction characterization. Register here to tune in and join more innovative discussions at the CRISPR Functional Genomics Symosium! bit.ly/3vcM6Nr

Thrilled to share our work published in Nature Communications! We've developed "sc-Tiling", which integrates a sc #CRISPR gene-tiling screen with #scRNAseq and protein structural analyses to identify regulatory mechanisms within a gene-coding region! nature.com/articles/s4146…

This has been a big collaborative effort over several years. Congratulations to everyone involve including: Matthias Schiedel, @Joe_P_B, Dr Hannah Bolland, Anthony K. N. Chan, Coco Laurin, @Katrina51963799, @PascalHeitel, Robert Paton, Will Pomerantz, Pomerantz Lab, Phil Biggin 🇪🇺, @Hammond_Lab.

Today we released a preprint biorxiv.org/content/10.110… where we take a step towards the next challenge: building a nanopore single-molecule PROTEIN sequencer! 😳 Awesome experiments by postdoc Henry Brinkerhoff of our #CDlab, augmented with MD simulations of AksimentievLab 1/x

BREAKING NEWS: The 2021 #NobelPrize in Physiology or Medicine has been awarded jointly to David Julius and Ardem Patapoutian “for their discoveries of receptors for temperature and touch.”

Drug combinations can overcome therapy resistance but the number of possible combinations is vast. Today we published @nature a study using pharmacological screens in cancer cell lines and multi-omics analysis to identify effective combinations in defined molecular backgrounds.

Today is the big day! The #T2T consortium is claiming victory and announcing that we have finally uncovered every last bit of the human genome! The papers are out today 🥳🧬 science.org/toc/science/37…

The 22Q2 data release is live on depmap.org! #depmapportal #depmap #openscience #cancerresearch

Cryo-EM can now break the atomic resolution barrier. Thanks to improvements in electron beam technology, detectors, and software. science.org/content/articl…

Today in partnership with Isomorphic Labs, we're sharing progress on the next generation of #AlphaFold. 🧬 Our new model greatly expands coverage of structure prediction beyond proteins to other key biomolecular classes. How could it help scientists? 🧵 dpmd.ai/alphafold-prog…

The UK medicines regulator approves the first therapy using CRISPR gene editing. Vertex Pharmaceuticals and CRISPR Therapeutics's Casgevy will treat the blood conditions sickle-cell disease and β-thalassemia #NBTNewsBeat nature.com/articles/d4158…

SGF29 regulates AML oncogene transcription and KAT2A chromatin localization in AML. ow.ly/P7SX50QGPBt #myeloidneoplasia

A new SAGA for AML: targeting SGF29 in AML ow.ly/ccuq50QGPU6 #myeloidneoplasia

#Leukemia is a class of aggressive blood disorders with low survival rates in some subtypes. Researchers have identified the gene, SGF29, as a potential target for suppressing leukemia progression. scim.ag/60t

Branched chemically modified poly(A) tails enhance the translation capacity of mRNA go.nature.com/3PzhhzM

Targeted Protein O-GlcNAcylation Using Bifunctional Small Molecules | Journal of the American Chemical Society Billy Ng CUHK Medicine #Protein #GlcNAcylation #Bifunctional #SmallMolecules pubs.acs.org/doi/10.1021/ja…

A new computational approach to de novo protein design enables the creation of drug-binding proteins with accurate design and prediction binding energy and specificity, researchers report in Science. 📄: scim.ag/6Ad

It was an absolute pleasure reconnecting with my esteemed mentor from Oxford, Prof. Stuart Conway, at UCLA. His invaluable career guidance continues to inspire my academic journey!

Out today: BioNumPy is a Python package for efficient array programming on biological data. nature.com/articles/s4159…