Coronavirus May Be a Blood Vessel Disease, Which Explains Everything by Dana Smith in Elemental Does endothelial dysfunction tie everything together? #COVID19. We have much to learn! @MRMehraMD elemental.medium.com/coronavirus-ma…

I’m on STEMI call tomorrow. I’ve been on call during blizzards and inauguration and the 4th of July but never during active riots. I haven’t given a single dose of lytic in my entire career. Now I’m wondering what is right for my team.

“the Surgisphere case raises a bigger question about how much access to key data each author and each journal should require. “The less access they have, the greater the chances that there will be errors, data fabrication, or outright fraud.” sciencemag.org/news/2020/06/t…

Low standard for #COVID19 and fool's gold in the #Surgisphere data sand box “They talk about propensity scores, this huge database from 169 hospitals, five continents, it sounds fancy, and people started latching to this study out of hope” Chaccour says"gu.com/p/exemb/stw

And even more strangely, for studies that claimed a massive feat of data integration in record-setting time, they had no biostatisticians listed as authors that might have helped pull all this data together. The Tiny Data Firm - Bloomberg bloomberg.com/news/articles/…

⁦Behi Rabbani, MD⁩ ⁦Rushi Parikh⁩ ⁦Gregg Fonarow MD⁩ ⁦Eric Topol⁩ ⁦Anthony Fauci 😷.⁩ Colchicine for the Treatment of Myocardial Injury in Patients With Coronavirus Disease 2019 #COVID19—An Old Drug With New Life? jamanetwork.com/journals/jaman…

Congrats to our inaugural #UCLABiodesign graduates! Tasked with driving health care innovation amid the unexpected #COVID19 pandemic, the team delivered far beyond expectations. Desert #UCLAInnovates Learn more about their advancements. ➨ ucla.in/2NOW6cz

Encouraging/hypothesis-generating data from GRECCO-19 re: Colchicine in COVID-19. More data forthcoming via large outpatient-based COLCORONA trial and UCLA Health inpatient-based COLHEART-19 trial in pts w/ cardiac injury. Please DM if interested in joining COLHEART-19.

Only 3 out of 4493 #COVID publications were randomized controlled trials. More than 1000 fold higher number of opinion pieces published. @califf001 Robert Harrington Adrian “WE NEED RCTS!” Hernandez David J. Cohen, MD, MSc Dr FM Eric D. Peterson Boback Ziaeian 🤦🏻‍♂️

COVID-19 Animation: Why some young and healthy people get more sick with... youtu.be/DDXlB_bP7Ko by Ayesha via YouTube

DAPA-CKD “also met all its secondary endpoints in CKD patients with and without type-2 diabetes (T2D), making dapagliflozin the first medicine to significantly reduce the risk of death from any cause in this patient population.” ⁦HFSA⁩ ⁦ astrazeneca.com/media-centre/p…

Number 1 🥇 in #California and top 4 in the nation. We’re proud to be named California’s top hospital once again by U.S. News & World Report (U.S. News & World Report): uclahealth.org/c-usnwr #BestHospitals

Expert review on the value of randomized trials and what common sense and observational data can inform. Gregg Fonarow MD Karol Watson Eric H Yang, MD UCLA Cardiology Fellowship Boback Ziaeian 🤦🏻‍♂️

#COVID19 You can run with a lie but you cant hide from the truth!! nejm.org/doi/full/10.10…

Reminds me of the chocolate classic in #NEJM nejm.org/doi/full/10.10…

Interesting study online in JACC from 5 major FFR studies (n=5129) - in pts with ACS lesions deferred with FFR >0.80 have higher MACE than in stable CAD. Most likely (IMO) due to vulnerable plaques despite being non-flow limiting. No difference in outcomes for treated lesions.

Acute myocardial infarction in the young with diabetes mellitus- national inpatient sample study with sex-based difference in outcomes internationaljournalofcardiology.com/article/S0167-…

OHCA in Los Angeles increased (+21%) while STEMI decreased (-7%) following the stay-at-home order. Increased OHCA (with lower ROSC and higher EMS response time) was not fully explained by STEMI reduction. 🔗 JAHA ahajournals.org/doi/10.1161/JA… #FOAMres #CardioTwitter ResusBot 🤖❤️⚡️

When suspecting heart attack or stroke, every minute counts so don't delay medical care due to COVID-19 and call 911. OHCA in Los Angeles increased (+21%) while STEMI decreased (-7%) following the stay-at-home order ahajournals.org/doi/10.1161/JA… Weiyi Tan, MD, MPH Gregg Fonarow MD UCLA Health