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Thrilled to share our new analysis from CheckMate 901! 🟡In N+ only metastatic UC, Nivolumab + chemo doubled complete response rate vs chemo alone (63% vs 34%) and prolonged PFS (HR 0.38) and OS (HR 0.58). ➡️A new horizon for a distinct subgroup. European Urology OncoAlert

Toxicity isn’t just a chart. It’s how someone feels at dinner! #ASCO25 #cancer #oncology @oncoalert ASCO Kate Sears Toni Choueiri, MD Emre Yekedüz Neeraj Agarwal, MD, FASCO 𝐂𝐡𝐚𝐧𝐝𝐥𝐞𝐫 𝐏𝐚𝐫𝐤 𝐌𝐃 𝐅𝐀𝐂𝐏 silke gillessen Petros Grivas Vivek Subbiah, MD TwoOncDocs Oncology Brothers LARVOL Dra. María Natalia Gandur Quiroga Sumanta K. Pal, MD, FASCO

Myriam Chalabi OncoAlert 🔑 Cannot over-emphasize that mismatch repair ✅MMR 🔬 testing should be done in 💯% of patients with colorectal cancers BEFORE any treatment decisions are made. There’s a reason why this was the 1st agnostic approval. OncoAlert #ASCO25

Time to Back to the ward. With more knowledge. More energy. More courage. Thank you #ASCO25 for 5 unforgettable days—full of learning, connection, and hope. See you soon 💙 ASCO OncoAlert #oncology #cancer Toni Choueiri, MD Emre Yekedüz Dana-Farber 𝐂𝐡𝐚𝐧𝐝𝐥𝐞𝐫 𝐏𝐚𝐫𝐤 𝐌𝐃 𝐅𝐀𝐂𝐏 Neeraj Agarwal, MD, FASCO

💡☝🏽Broad panel-based NGS genomic testing🧬for non-metastatic #ColorectalCancer should be in the guidelines: We have ▪️PIK3CA consider testing statement➡️Aspirin💊 Don’t miss your ▪️MSS POL-E patient🟰immunotherapy💉 BRAF, HER2, MSI, & 🔜KRAS for adjuvant➕trials. OncoAlert

🧬 Which genes matter most in breast cancer testing? ESMO recommends a focused panel (BRCA1/2, PALB2, RAD51C/D, BRIP1, TP53) for routine germline testing in BC. ESMO - Eur. Oncology G Curigliano MD PhD FabriceAndre #esmo OncoAlert Oncology Brothers dailyreporter.esmo.org/news/experts-r…

#LiquidBiopsies👇🏽this is 🆒! 💡Less about the assay but more about the approach/science. For patients getting liquid biopsies (#ctDNA), good idea by companies reporting other relevant biomarkers. ✔️Secondary germline🧬 ✔️Pharmacogenomics💊 ✔️HLA🩸 ✔️Viral e.g. HPV🦠 OncoAlert

🧬 Precision oncology in India is undergoing a silent revolution. From react & respond ➡️ predict & prevent. Here’s how we’re rewriting the rules of cancer care. 👇 #CancerDiagnostics #Genomics #India

Every cancer patient deserves a complete diagnosis.

From the diary of an oncologist -