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This paper is insane 🤯 for a few reasons. The first being they experimentally evolved a yeast into a multicellular organism. The second is that the review process took longer than the evolution process 🤦🏻‍♂️ nature.com/articles/s4158…

Super excited to share our newest study of mechanical properties of hair follicle stem cells and manipulate mechanical forces to activate hair growth by using a microRNA in collaboration with Dr. Srikala Raghavan Jie Yan Kathleen J Green pnas.org/doi/10.1073/pn…

Cells can pass proteins and RNA to each other through tubes that act as a channel between their membranes. elifesciences.org/articles/84391…

I’ll be presenting my work on sebaceous gland development at #ISSCR2023 today from 10.45 AM. Stop by poster #1000, say hi to me, and learn about my work in Yi Lab. Looking forward to some interesting discussions!

Out today: SCENIC+ is a comprehensive toolbox for inferring and analyzing enhancer-driven gene regulatory networks (eGRN) using single-cell multiomic data. @steinaerts Seppe De Winter Carmen Bravo nature.com/articles/s4159…

Join us !!!

Happy to share two of our newest studies. In the study of MOF and H4K16ac, we found essential functions of MOF in controlling mitochondria and primary cilia in the skin. The regulation is prominently mediated at gene promoters. nature.com/articles/s4146…

In our analysis of single cell transcriptome and open chromatin during aging, Chi Zhang found the transcriptome of hair follicle stem cells is influenced by the hair cycle whereas their niche is less sensitive. frontiersin.org/articles/10.33…

Chandrayaan-3 Mission: 'India🇮🇳, I reached my destination and you too!' : Chandrayaan-3 Chandrayaan-3 has successfully soft-landed on the moon 🌖!. Congratulations, India🇮🇳! #Chandrayaan_3 #Ch3

Chandrayaan-3 Mission: The image captured by the Landing Imager Camera after the landing. It shows a portion of Chandrayaan-3's landing site. Seen also is a leg and its accompanying shadow. Chandrayaan-3 chose a relatively flat region on the lunar surface 🙂

BREAKING NEWS The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.

Very excited to share our newest tool: scHolography for reconstruction and quantitative analysis of spatial neighborhoods. Fantastic work by YCF and collaboration with Rosemary Braun. Visit github.com/YiLab-SC/scHol… for tutorials. genomebiology.biomedcentral.com/articles/10.11…

#NewPaperAlert Excited to present our latest J Cell Science paper demonstrating Hominini-specific regulation of cell cycle by stop codon readthrough of FEM1B bit.ly/MdNA Noor Akhtar Anumeha Singh Lekha E M Dhruba Dey Sangeetha Devi Kumar Arpan Das 😷 Sandeep M Eswarappa

BREAKING NEWS The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.

Say good morning to our new medicine laureate 🎉 Gary Ruvkun was woken up in the early hours to the news he had been awarded the 2024 Nobel Prize in Physiology or Medicine. Stay tuned for our interview with him, coming soon.

2024 #NobelPrize laureate in physiology or medicine Victor Ambros was born in 1953 in Hanover, New Hampshire, USA. He is now Silverman Professor of Natural Science at the UMass Chan Medical School, Worcester, MA. umassmed.edu/cancer-center/…

Congrats to YCF to successfully defend her beautiful thesis work of single cell genomics of the skin. Thanks Kathleen J Green @yogeshgoyallab and Rosemary Braun. Due to Driskill Graduate Program in Life Sci procedures, Cady will publicly present her work next Wednesday. Let celebration begins!

Excited to share our new work in collaboration with Jie Yan and The Green Lab We 1) determined 20pN force through E-cad is sufficient to activate PIEZO1; 2) quantified Ca dynamics and identified their downstream targets in hair follicle stem cells. science.org/doi/10.1126/sc…

Congrats to YCF to graduate from the DGP in 4 years after joining our lab in 2021. Cady is our first ever graduate student at Northwestern, and she has heralded a new era of single cell spatial transcriptomics in the lab. We wish her the best and continued success at SF!