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Mediastinal grey zone lymphoma, classic Hodgkin lymphoma-like: 🩸Confluent pleomorphic cells admixed with eosinophils & dense fibrotic stroma 🩸Uniform strong expression of CD20, PAX5 & at least one additional B marker (CD19, CD79a, BOB1, OCT2) 🩸CD30+ #hemepath #lymsm

Primary cutaneous anaplastic large cell lymphoma➡️ 🩸Rearrangement of the DUSP22 locus at 6p25.3 occurs in 20-25% of the primary cutaneous form, these tend to show more epidermotropism #PathTwitter #dermpath #hemepath #surgpath #lymsm #MedTwitter

Follicular lymphoma with abundant extracellular eosinophilic material, mimicking amyloid deposition: An unsual variant to be aware of #hemepath #lymsm #pathtwitter #MedEd #SoMe Check a similar but more prominent case by Sanam Loghavi, MD صنم لغوی 🔬🧬 Blood Journal➡️ ashpublications.org/blood/article/…

Another case I got today where LEF1 and SOX11 made the case stronger for Burkitt lymphoma #hemepath #lymsm #pathX #pathTwitter #MedX #MedTwitter #SoMe

Looks like a bone marrow aspirate, but it’s really peripheral blood. Chronic myeloid leukemia. #pathology #pathtwitter #pathx #hemepath

Pathologists! Check out this enlarged lymph node with a florid proliferation of monocytoid B cells, suspicious for lymphoma, but with no immuno phenotypic evidence of clonality. Turned out to be CMV lymphadenitis with many classic viral inclusions.#Hemepath #CMV

Pathologists! Per WHO 5th edition, the term “hairy cell leukemia variant” is eliminated; most such cases are now classified as splenic B cell lymphoma/leukemia with prominent nucleoli (SBLLPN). Here is an example of SBLLPN.

Great example of cell morphology in B ALL! OhioStatePath #hemepath

🩸Burkitt lymphoma with granulomatous background is a rare and underrecognized variant that expands the list of lymphomas with granulomatous presentation (mainly classic Hodgkin lymphoma and T-cell lymphomas). 🩸Few of these cases have been reported in the litterature. 🩸These

A rare case of Dasatinib-related "fluid overload- associated large B-cell lymphoma" (FO-LBCL) involving the preicardial fluid: 🩸FO-LBLCL is an HHV8 and EBV-negative primary effusion-based lymphoma, frequently associated with fluid overload related to diseases of the heart,

Just added! Virtual attendance option now available for our #DigitalPathology Workshop! Learn about the latest #pathology tech and techniques. Click for info, and to register for the workshop on 9/12 Ohio State #PathTwitter go.osu.edu/2024pathcme

If you diagnose a nodal T-cell lymphoma with these features: -Morphology is blastoid -No monotypic pattern of TRBC1 by flow cytometry analysis -No TCR gene rearrangement by PCR Add a marker of cell immaturity like TDT, CD34, CD117 etc, even if the clinical features are not

Rare cases of FL/ DLBCL with BCL2 and IRF4 rearrangements exist, and should not be confused with large B-cell lymphoma with IRF4 rearrangement. FL/ DLBCL with BCL2 and IRF4 rearrangements typically show triple expression of CD10, BCL6 and MUM1 by IHC stains. FL/ DLBCL with

A great turnout for our #DEI #lunchandlearn event! We enjoyed robust discussion and helped foster a sense of community, belonging and inclusion. OhioStatePath Anil Parwani

So excited to invite you to our open house sessions! Please join us to chat with our great residents and learn more about our amazing program Ohio State OhioStatePath #ohiostatepathology #pathtwitter #pathmatch25

Reactive intralymphovascular immunoblastic proliferations➡️ Recurrent theme in #Hemepath consultations sent from other #surgpath services Cases with these proliferations are typically sent by #GIpath (most commonly in resected appendices or GI segments for obstruction) or

Congratulations Lewis! Well deserved! 👏🏻👏🏻

classic morphological 🔬 findings of CML (BCR::ABL1 +) in honor of #WoldCMLDay 09/22 Bone marrow: 1️⃣Left shifted myeloid hyperplasia with eosinophilia 2️⃣Micromegakaryocytes 3️⃣See blue histiocytes #hemepath #leusm #CML

Pathologists! Here is a classic case of Burkitt lymphoma, EBV+, presenting as a nasopharyngeal mass in a little boy. Fortunately, therapy is good and the prognosis is favorable. #Hemepath #Lymphoma

We’re thrilled to see our very own Holli Loomans-Kropp featured in the latest CGA-IGC #podcast episode released on #LynchSyndromeAwarenessDay! Tune in to hear about the LINEAGE consortium and building impactful research collaborations. The Ohio State University College of Medicine cgaigc.com/podcast/episod…