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AlphaRING: Missense Variant Classification via Protein Modelling and Residue Interaction Network Analysis • The study introduces AlphaRING, a publicly available tool combining AlphaFold2 with residue interaction network (RIN) analysis to classify missense variant pathogenicity.

Comparative Evaluation of Methods for the Prediction of Protein–Ligand Binding Sites Journal of Cheminformatics 1. This study benchmarks 13 state-of-the-art protein–ligand binding site prediction methods across three decades, introducing the new LIGYSIS dataset with 30,000 biologically relevant

fyi, my alternate #KLEBS2024 flash talk slide #Klebsiella #Kaptive

Starting day 2 of #KLEBS2024 with a session about #klebsiella and #OneHealth - excellent introductory keynote given by Marit Hetland

Starting day 3 of #KLEBS2024 with a session on Genomics and Evolution with excellent presentations given by David Aanensen , Olaya Rendueles , melissa j martin , Ben Vezina , Anna Weber

Absolute gold-standard work here. For your #Acinetobacter and #Klebsiella needs, upgrade to Kaptive 3 today! 1) Accurate capsule predictions 2) Sets a precedent for how to build a systematic and robust capsule database 3) ~1 second per genome biorxiv.org/content/10.110…

It would be a fun change of pace to do something so different for us. 😄 As fun as Gothic Horror has been, I'd love to explore other styles and tones!

Our new paper on the global epi of IMP carbapenemases. We originally called this paper: ‘Planet of the IMPs’ as IMPs are now everywhere. We found IMP variant-specific distributions across species, plasmids, mobile elements and geography medrxiv.org/content/10.110…