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Featured today by MSK Library: Pan-cancer multi-omic model of LINE-1 activity reveals locus heterogeneity of retrotransposition efficiency #CancerGenomics #MultiOmics #LINE1 #Retrotransposition #GenomicResearch #PanCancerStudy #Bioinformatics #MolecularOncology

Final version of David Ting Benjamin D. Greenbaum Cancer Discovery paper is online. So many interesting roles attributed to the LINE-1 protein ORF1p in #PancreaticCancer recently, from a circulating biomarker to an “immune mask” protecting against tumor rejection.

Thank you Memorial Sloan Kettering Cancer Center for highlighting the work of our lab & our great collaborators!

#mDNASRC is back and stronger than ever after 30 years! Discover how transposable elements shape our genomes and impact health, featuring keynote speaker Jef Boeke, alongside organizer Benjamin D. Greenbaum, and more. Save your space: hubs.ly/Q03h6Nl90

Great article in Science Magazine mentioning our efforts to target the #darkproteome! Nice to see our colleagues David Ting Daniel De Carvalho Marty Taylor, MD PhD and the work of ROME Therapeutics highlighted as well 👇 science.org/content/articl…

#mDNASCR is going to be a great meeting - if you are interested in this important and growing field come out!

Looking forward to #AACR25! If you want to learn more about transposable elements in cancer, our educational session is at 10 am on Saturday 4/26! AACR Benjamin D. Greenbaum

Come check out our session tomorrow #AACR2025 transposable elements in cancer - one of the most interesting topics there is! 🔥 With Kate Chiappinelli @chiappinellilab.bsky.social & Ting Wang - 4/26 at 10 am AACR 👇👇👇

Attending the #AACR25 session on Transposable Elements in Cancer? Read recent work in Cancer Discovery by session speaker Benjamin D. Greenbaum: LINE-1 ORF1p Mimics Viral Innate Immune Evasion Mechanisms in Pancreatic Ductal Adenocarcinoma doi.org/10.1158/2159-8…

Call for abstracts! #mDNASRC is in beautiful Porto this year! Organizers Benjamin D. Greenbaum, ZZ Zhao Zhang, John LaCava, and Vera Gorbunova may select you for a poster session or short talk. You can even register now and submit your abstract later. Save your space: bit.ly/3F0chBY

AI and Machine Learning in IO: Arnav Mehta, Benjamin Greenbaum, and Elham Azizi will address this topic in an #AACRIO25 webinar (June 11), moderated by Elana Fertig and Dana Pe’er. Learn more: brnw.ch/21wSu5G Arnav Mehta Benjamin D. Greenbaum Elham Azizi dana_peer

Grateful & humbled to make the 2025 #TIME100HEALTH list with such inspiring global health leaders. This honor reflects my team, who are unrelenting in their efforts to advance new treatments for pancreatic cancer!

Featured today by MSK Library: Mis-splicing-derived neoantigens and cognate TCRs in splicing factor mutant leukemias dx.doi.org/10.1016/j.cell… #Neoantigens #SplicingMutations #LeukemiaResearch #CancerImmunotherapy #TCellReceptors #HematologicMalignancies #PrecisionOncology

AI and Machine Learning in IO: Arnav Mehta, Benjamin Greenbaum, and Elham Azizi will address this topic in an #AACRIO25 webinar (June 11), moderated by Elana Fertig and Dana Pe’er. Learn more: brnw.ch/21wSGyU Arnav Mehta Benjamin D. Greenbaum Elham Azizi dana_peer

Our article, “Trait-space patterning is dictated by the tempo and mode of mutation,” co-authored with Stephen Martis and David Schwab, is out in PNAS! We show how mutation processes shape evolution, with relevance to bacteria–phage interactions. pnas.org/doi/abs/10.107…

Make sure to register for this great meeting on Mobile Elements with a focus on mechanism and disease impact. It will be in beautiful Porto with an amazing speaker line up on this timely topic 👇👇👇🔥🔥🔥

Awesome work by our Stephen Martis & Trevor GrandPre! They show how intrinsic vs extrinsic mutational processes can have very different phenotypic consequences. Cool theory with clear applications for our science - proud Stephen Martis is in our lab & excited to explore

AI and Machine Learning in IO: Arnav Mehta, Benjamin Greenbaum, and Elham Azizi will address this topic in an #AACRIO25 webinar (June 11), moderated by Elana Fertig and Dana Pe’er. Learn more: brnw.ch/21wT6nw Arnav Mehta Benjamin D. Greenbaum Elham Azizi dana_peer