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Great few days with the McEwan lab at ADPD2022 - hope to be back next year! #TogetherAtADPD

Enjoying Gothenburg before #ADPD2023! Fantastic to be here and see some sun too 😄 @w_mcewan lab and friends UK Dementia Research Institute 🤩

Super excited to share our latest paper on a novel targeted protein degradation technology, now out in Cell. We introduce RING-Bait technology, an innovative approach to selectively target and degrade intracellular protein aggregates (1/7) cell.com/cell/fulltext/…

The UK DRI's @w_mcewan & Leo James' Lab (@MRC_LMB) have developed new therapies that selectively remove aggregated tau proteins - harnessing the unique capabilities of a protein called TRIM21. The treatment improved symptoms of neurodegeneration in mice👉buff.ly/47ogpFG

Researchers from @MRC_LMB in Cambridge, England and UK Dementia Research Institute at Cambridge University have developed new potential therapies that selectively remove the aggregated tau tangles to treat #Alzheimersdisease. Learn more: hubs.li/Q02PRGyg0

Exciting new research co-led by @w_mcewan harnesses the unique capabilities of the protein TRIM21 to selectively remove aggregated tau from the brains of mice The team say this approach could avoid any potential side-effects of eliminating normal tau👉buff.ly/47ogpFG

Targeting intracellular tau tangles with the active domain of a ubiquitin ligase mopped them up rapidly in tauopathy mice. #alzheimersdisease UK Dementia Research Institute, @MRC_LMB ow.ly/eNMm50Ts1MZ

Episode 8 of the ParAqua podcast features Professor Claire Gachon from the Museum of Natural History in Paris. We discuss her research on parasitism and the impacts it can have on the emerging algal aquaculture industry linktr.ee/paraquapodcast ParAqua COST Action Ana Gavrilović

Check out episode 9 of The ParAqua Podcast featuring Jonas Mauch from IGB Berlin (now on Bluesky) We discuss his PhD research into the effects of climate change and changing lake ecology on the invasive Quagga Mussel linktr.ee/paraquapodcast ParAqua COST Action

Our review is out now in Neuron! We provide an updated overview of the links between autophagy, ageing, and age-related neurodegeneration. A collaboration between the Rubinsztein and @VIKorolchuk labs that was very enjoyable to work on 🤓 cell.com/neuron/fulltex…