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Congrats Hosung Bae Sunhee Jung Johnny and co-authors for their work! Cell sciencedirect.com/science/articl…

The Lurie Cancer Center (LCC) went thru competing renewal of NCI designation. For a 2nd time we got "exceptional" ranking. The NCI site visit team gave a "perfect exceptional" (equivalent to 10). LCC is one of few in the nation and the only one in IL to ever achieve exceptional status.

Congratulations to Renata Goncalves and everyone who contributed to this amazing work! CoQ imbalance drives reverse electron transport to disrupt liver metabolism Gökhan Hotamışlıgil nature.com/articles/s4158…

Excited to share our latest paper led by Renata Goncalves Renata Goncalves: CoQ imbalance drives reverse electron transport to disrupt liver metabolism. nature.com/articles/s4158… We uncover how altered CoQ redox balance triggers RET and rewires hepatic metabolism to offer

New paper alert! Huge congrats to my graduate student Jesse Velasco on his first author publication in physiological reports physoc.onlinelibrary.wiley.com/doi/10.14814/p… 1/n

The geroprotectors trametinib and rapamycin combine additively to extend mouse healthspan and lifespan | Nature Aging nature.com/articles/s4358…

Exciting new work by sancak in Science Advances showing how mitochondrial Ca2 fluxes control branched chain amino acid metabolism. Mitochondrial Ca2 is not just about the TCA cycle!

Cysteine depletion triggers adipose tissue thermogenesis and weight loss go.nature.com/43uySjS

Many cool articles in the Metabolist this month. metabolist.wordpress.com/2025/06/03/met…

Happy to share our latest paper showing that deletion of adipose-derived Isthmin-1 leads to fatty liver and elevated ceramides. Congrats to first author Saranya Reghupaty and all the co-authors! Molecular Metabolism Stanford Pathology Stanford Diabetes Research sciencedirect.com/science/articl…

🎉 Something exciting just landed in the mail! Thrilled to share that one of our illustrations has been featured on the cover of Genes & Development Genes & Development ! Big congratulations to Sihem Cheloufi and her incredible team for their groundbreaking science. It was such a joy

Excited to unveil Boltz-2, our new model capable not only of predicting structures but also binding affinities! Boltz-2 is the first AI model to approach the performance of FEP simulations while being more than 1000x faster! All open-sourced under MIT license! A thread… 🤗🚀

Happy to see our highlight out in Current Biology discussing new findings related to NADH and FSP1 compartmentalization in ferroptosis. Lead by two terrific postdocs amalia megarioti and Kirandeep Deol! 🤩 cell.com/current-biolog…

Excited to share our latest study from the Manning Lab. We have developed and characterized a novel mouse model lacking the five AKT phosphorylation sites on the TSC2 protein, which are critical for AKT-mediated activation of mTORC1 signaling.

📣Don't forget to register and submit your abstract for short talk consideration at #RedoxBio25 The chairs would love to have you on board and look forward welcoming some new and familiar faces in sunny Mexico. 🇲🇽🌞 To Register and Submit your abstract: bit.ly/45Qk3tb

My lab's first paper is out in nature. We show that lipoprotein uptake protects tumors from ferroptosis by delivering the lipid antioxidant α-tocopherol. Surprisingly, tumors use sulfated glycosaminoglycans—not canonical receptors—to capture lipoproteins. nature.com/articles/s4158…

Out today from ThePerryLab, our work suggesting how exposure to high fructose in pregnant mice or developing neonates directly affects neurodevelopment. In nature nature.com/articles/s4158… Memorial Sloan Kettering Cancer Center Weill Cornell Medicine funded by NIH NIH Common Fund cc: Jay Bhattacharya, MD, PhD

New paper alert! We report in Cell Metabolism how serine regulates skin stem cell fate. Congratulations to everyone involved! cell.com/cell-metabolis…

PhD opportunity (open for UK-Students only): Interested in PhD project where you investigate environmental factors driving lung cancer inequalities? Deadline : 30th June 2025 Please share! findaphd.com/phds/project/c…

China is on course to overtake the United States as the world’s largest contributor to research go.nature.com/3HLpoIh