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Despite Nektar’s share price shooting up as much as 175% on Tuesday, William Blair maintained that “there is an absence of clear differentiation” for rezpegaldesleukin in the atopic dermatitis space. #pharma #biospace hubs.ly/Q03ty97p0

Mike Davis previously worked as clinical team leader at the FDA’s Division of Psychiatry before serving as chief medical officer for Usona Institute, a research organization advancing psychedelic science. #CDER #FDA #biospace hubs.ly/Q03tybkV0

The FDA is assessing the need for “further regulatory action” on Sarepta’s Duchenne muscular dystrophy gene therapy in the aftermath of two patient deaths, though the regulator has not yet specified what action this could be. #FDA #regulatory #biospace hubs.ly/Q03tybPW0

.Gilead Sciences is betting up to $750 million on Kymera’s anti-CDK2 molecular glue for solid tumors, while Sanofi elected to move forward with another protein degrader from the biotech, designed to target immune-mediated diseases. #pharma #biospace hubs.ly/Q03tydtF0

.Eli Lilly and Company's tirzepatide is expected to be worth $62 billion annually by 2030, according to Evaluate. That valuation would be three times larger than what AbbVie's blockbuster Humira ever achieved. #GLP1 #obesity #biospace hubs.li/Q03tydVW0

In the latest installment of his column, Kaye/Bassman’s Michael Pietrack shares five ways leaders can help their teams after a layoff, from acknowledging emotions to reestablishing culture. #leadership #biopharma #biospace hubs.li/Q03tyFD70

Tapping into the hidden job market can be challenging but is important in today’s employer-driven market. Three talent acquisition experts share tips for accessing hard-to-find roles. #hiddenjobmarket #biopharma #biospace hubs.li/Q03tyS150

Roughly a month after sharing that it would cut about half of its workforce, Leap Therapeutics has announced it will axe 75% of its staff over the next two months. Get the details in our layoff tracker. #layoffs #biopharma #biospace hubs.li/Q03tz3WX0

The newly appointed members of the CDC’s influential vaccine committee meet Wednesday and Thursday under an unusually rapid timeline, with unexpected topics on the agenda. #CDC #vaccines #biospace hubs.li/Q03tBWwt0

Writing in JAMA, four former governmental officials warn that the Trump administration’s involvement in delaying the approval of Novavax's COVID-19 vaccine could indicate a politicization of the drug approval processes that could ‘imperil public health.’ #FDA #drugapproval

Are long R&D cycles, overwhelming literature reviews, or patent bottlenecks slowing your path to innovation? In the fast-evolving life science landscape, AI is no longer a luxury, it’s a necessity. Miss our webinar with Patsnap yesterday? Watch it on demand now! #webinar #AI

Given today’s available local talent pool, biopharma companies are less likely to turn toward international job candidates, according to a talent acquisition expert. Findings from two recent BioSpace LinkedIn polls underscore the issue. #biopharma #hiring #careers #biospace

Peter Marks, who headed the FDA’s Center for Biologics Evaluation and Research before being forced to resign in March, said the agency’s new risk-based COVID-19 vaccine framework contradicts the current administration’s push for transparency and gold-standard science. #CBER #FDA

Bayer subsidiary BlueRock Therapeutics is laying off around 50 employees across all of its sites, a company spokesperson confirmed to BioSpace on Wednesday. The workforce reduction is in line with the biotech’s push to “streamline our pipeline and organizational structure” and

Without providing further context, HHS Secretary Robert F. Kennedy Jr. says that Gavi needs to “start taking vaccine safety seriously” by considering “the best science available.” #vaccines #HHS #biospace hubs.li/Q03tP82z0

Flagship Pioneering’s ProFound Therapeutics will use its proprietary technology to mine the expanded proteome for novel cardiovascular therapeutics. Novartis has promised to pay up to $750 million per target, though it has not specified how many targets it will go after.

Susan Monarez, already acting director of the CDC, said during her confirmation hearing that she sees no causal link between vaccines and autism. #CDC #vaccines #biospace hubs.li/Q03tRq_p0

Minovia’s lead product is MNV-201, an autologous hematopoietic stem cell product that is enriched with allogeneic mitochondria. #biotech #biospace hubs.li/Q03tW4WZ0

Jefferies analysts called the proxy filing, which is a standard disclosure after a merger agreement, “much more intriguing than normal” given the regulatory turmoil it revealed. #merger #biospace hubs.li/Q03tW4W70

🌟 Know a rising star in the life sciences? Nominate them for BioSpace’s 40 Under 40, honoring young professionals driving innovation and change in biotech and pharma. Submit your nomination today: hubs.li/Q03rmcfR0 #biotech #lifescineces #biospace40under40 #biospace