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#clinicalquestion How does Finerenone decrease afib incidence..? jacc.org/doi/10.1016/j.… JACC Journals John Mandrola, MD Sensible Medicine #EPpeeps

One of the most important business lessons to UNLEARN after your medical training is how to be a good soldier. The same attributes that made you flourish as a resident can become a liability as an attending. Learn the mindset you should adopt instead: docempowered.com/the-business-l…

For those wondering why a simple doctor’s visit takes so long… Or why medical offices can seem so inefficient… Here’s the journey of a single patient chart… and remember only 1/3 of the quality metrics have any clinical relevance… before we’ve even had a chance to talk

In our increasingly concentrated healthcare market, physician noncompetes no longer serve a rational economic purpose. More states are waking up to this fact and limiting or banning them. Srihari S. Naidu, MD ACC Advocacy Dutch Rojas John P Erwin III MD MBA MACC (#BigPoppy ) jacc.org/doi/10.1016/j.…

The #EAS2025 Congress has officially begun, and it kicked off with a crystal-clear, no-nonsense message: LDL-C is CAUSAL This slide leaves no room for ambiguity: •Pathophysiology: LDL is required for plaque development. •Genetics (including familial hypercholesterolemia):

Prof Kausik Ray FMedSci #EASCongress2025 🫀LDL/ApoB is atherogenic & our target of Tx 🫀Time matters: cumulative exposure matters- start early& maintain 🫀multiple Tx effective & combination effective: LDL ⬇️ 🫀Post MI: why stepwise? Get LDL ⬇️ early - would ⬇️ MACE

Nice Review of options to treat ATTR-CM Tafamadis vs. Acoramidis (Stabilizers)? -- no idea, prob won't ever have trial.. likely whichever insurance will cover Silencer vs. Stabilizer vs. Both? JACC Journals jacc.org/doi/10.1016/j.…

Need help from the Preventative Cardiologists and Lipidologists out there. Trying to get Arup to change "abnormal" result for ApoB < 60. (ie: take away the red flag when Apob is at goal of < 60!) Roger Blumenthal International Lipid Expert Panel (ILEP) National Lipid Association Dr. James Underberg National Lipid Association

Just published NEJM A randomized trial of Semaglutide (Ozempic) vs Tirzepatide (Mounjaro, Zepbound) at max doses demonstrates superiority of the latter for weight loss nejm.org/doi/full/10.10…

Impressive is the current administration’s choice of ⁦Jay Bhattacharya⁩ ⁦Marty Makary MD, MPH⁩ and ⁦Vinay Prasad MD MPH⁩ to be in key healthcare leadership roles. US health, especially non-communicable disease, is in need of sweeping change. thefp.com/p/ahead-of-the…

🚑 Shock Talk Just Got Real! 🎧 418. CardioNerds x The Cardiogenic Shock Working Group: LV Unloading in AMI Shock Gurleen Kaur, MD Rachel Goodman Navin Kapur, Shashank Sinha, MD, MSc, FACC, FAHA, FHFSA Rachna Kataria, MD break down updated AMI shock guidelines & the Class 2A role of transvalvular flow pumps cardionerds.com/418-cardionerd…

This one slide could be my entire 40 min lecture on medical evidence (iii and viii are my favorites)

The HITECH Act exemplified regulatory capture. EHRs were mandated and subsidized to the tune of billions. Here are but a few of the downsides of EHRs: • Decreased the productivity of a profession already in short supply, physicians • Physicians spend hours on the EHR for

SGLT2 inhibition initiation in the acute hospital setting? This trial showed significant benefit — REGARDLESS of ejection fraction — safe, and with incrementally added benefit when started early. EMPULSE Trial, Nature Medicine, 2022 ♥️

LP(a) is a risk enhancer.. why should this set off diagnostic testing cascade? Aggressive risk factor modification. Drive ApoB down. Don't do unnecessary testing! jacc.org/doi/10.1016/j.… JACC Journals John Mandrola, MD

🚴‍♂️🏊‍♂️🏃‍♂️ Sept 27th, I’m taking on the Rock Hall Waterman’s Half Ironman,to raise money for SJMCTowson Donations go directly to support pt care. Thank you for your support! #JustGiving justgiving.com/campaign/jerem…

In absence of low EF, angina, ventricular arrythmia, in pts with rapid revasc, not sure there is any benefit to BB any longer. Need to change our registry databases, otherwise we will continue to have to utilize BB post MI to avoid "penalties" jacc.org/doi/10.1016/j.…