Now Online! 🗞️#Andexanet alfa versus non-specific treatments for #intracerebral #hemorrhage in patients taking factor Xa inhibitors — Individual patient data analysis of ANNEXA-4 and TICH-NOAC. journals.sagepub.com/doi/abs/10.117… David Seiffge Bernhard Siepen Stroke Research Center Bern

New non-randomized comparidon of andexanet alfa and usual care (i.e. PCC and/or TXA) in patients with factorXa-inhibitor- ICH - high rate of continuous bleeding (aka haematoma expansion) with usual care. Andexanet was associated with lower incidence of HE Stroke Research Center Bern Bernhard Siepen

Bernhard Siepen from Stroke Research Center Bern presenting the MAX-ICH trial (supported by Schweizerische Herzstiftung ) at the European Stroke Org ICH academy at #ESOC2024 in Basel - the next step for ICH treatment?

In our latest study published today in European Stroke Org , we analyzed the safety of those more liberal decisions. A team effort by Philipp Bücke Simon Jung Johannes Kaesmacher David Seiffge Martina Göldlin Morin Beyeler, MD, PhD Urs Martin Fischer Thomas Meinel journals.sagepub.com/doi/10.1177/23…

Excellent start to #ESOC with lively discussions after extraordinary talks at the #ESO ICH Academy, thanks to the organizers! It was a pleasure chairing…. Laurent Puy, Andrea Morotti,and European Stroke Org

Had a honor to moderate the session of the #stroke #services together with Manuel Requena from Spain - we had impressive speakers from 🇩🇪 , 🇦🇺 ,🇨🇭 Mobile stroke units and even flying teams: all leads to an improvement of the mRS European Stroke Org #ESOC2024

The ANNEXa-I primary results manuscript is now available NEJM. nejm.org/doi/full/10.10… #stroke #neurotwitter @McMasterStroke McMaster University Department of Medicine PHRI.ca Population Health Research Institute 🇨🇦 David Seiffge Else C. Sandset Mike Sharma Andrew Demchuk Carlos Molina Professor Hanne Christensen @robinlemmens

So honoured our planned MAX-ICH pilot study 🧠🩸 received the IAM award 2024 for best research project. Thanks to European Stroke Org and organisers Laurent Puy, Andrea Morotti & Thorsten Steiner. Would not be possible without David Seiffge @researchbern 🙏🏻

Congratulations to David Seiffge & Urs Martin Fischer representing European Stroke Org in the board of directors and as the incoming president. We can't wait to see the impact you'll make. Proud to have you on our team!

Do all patients with ICH need treatement at a hospital with neurosurgery? Probably not: this large prospectice study from Catalunya showed no difference in outcome according to hospital type neurology.org/doi/10.1212/WN… Treatment of ICH is as easy as ABC neurology.org/doi/10.1212/WN…

#FlashbackFriday ! 🗞️#Andexanet alfa versus non-specific treatments for #intracerebral #hemorrhage in patients taking factor Xa inhibitors — Individual patient data analysis of ANNEXA-4 and TICH-NOAC. journals.sagepub.com/doi/abs/10.117… David Seiffge Bernhard Siepen Stroke Research Center Bern

Latest updates in the gudielines of ICH management 🧠🩸by Bernhard Siepen at Bern Stroke & Brain Health Symposium. Andexanet alfa in DOAC-associated ICH showed lower rates of HE - but this did not translate into better functional outcome ❌️

That’s a great programme connecting stroke enthusiasts! We were lucky to welcome many brillant young doctors at Stroke Research Center Bern Insel Gruppe over the last years - please get in touch if you are interested Urs Martin Fischer Thomas Meinel European Stroke Master Martina Göldlin Bernhard Siepen Espen Saxhaug Kristoffersen

Globally, intracerebral haemorrhage causes more loss of healthy life years than ischaemic stroke. We must prioritise ICH to reduce its burden through public health interventions, research, and improved healthcare. See our open access World Stroke Org factsheet 👇🏻

#ESOC25 here we come ... ! Team Stroke Research Center Bern looking forward to the best science and highlight of the year. European Stroke Org Urs Martin Fischer

🧠 New! The ESJ ICH Supplement covers clinical updates on anticoagulation-related intracerebral haemorrhage. From reversal strategies to post-ICH management—read the latest insights: 🔗 ow.ly/ZJ0s50VWrAC #ESOC2025 #StrokeCare #ICH #Neurology #VoiceOfStroke #StrokeTwitter

European Stroke Org special issue on OAC-ICH was just published: ow.ly/ZJ0s50VWrAC Together with Thorsten Steiner and a team of renowned experts, we summarize latest evidence on several aspects of OAC-ICH Management Bernhard Siepen Ashkan Shoamanesh Sven Poli Espen Saxhaug Kristoffersen Stroke Research Center Bern

Essential reading for stroke specialists – the European Stroke Journal ICH Supplement From reversal strategies to post-ICH management—read the latest insights: 🔗 ow.ly/ZJ0s50VWrAC #ESOC2025 #StrokeCare #ICH #Neurology #VoiceOfStroke #StrokeTwitter