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New #Cas9 variant makes #genome editing even more precise: researchers Max Planck Society Universität Halle (inaktiv) develop more specific #CRISPR-Cas9 gene scissors mpg.de/14538884/new-c…

New highly specific Cas9 variant (R63A/Q768A) out Nature Chemical Biology. Congrats to all co-authors! nature.com/articles/s4158…

I love this theory! You have your greatest ideas while you're 'bored', as in not busy doing other things. ted.com/talks/manoush_…

Our first #CRISPR screening paper is out! We identify X-chromosomal genes that drive sex differences in embryonic stem cells. Congratulations to Oriana Genolet and everyone else who contributed Anna Alessandra Monaco Michael Boettcher! For Tweetorial see thread below. biorxiv.org/content/10.110…

Today we report the continuous evolution of ABE8e, a new adenine base editor that is ~600x faster than previous ABEs, enabling compatibility with all 8 tested Cas9 and Cas12 variants, and much more efficient editing, including at therapeutic targets. (1/2) drive.google.com/file/d/11wRpf_…

Prime genome editing in rice and wheat go.nature.com/2x2KIVi

Our lab's recent work on harnessing RNA-targeting CRISPRs for forward transcriptomic screens in human cells is now published Nature Biotechnology. We hope this platform will be of broad utility for geneticists and biologists with applications for diverse phenotypes and diseases.

Very proud of this review by our Verena Mutzel now out in #Bioessays Wiley! We dissect old and new concepts proposed to drive the onset of random X-chromosome inactivation from a systems biology perspective.

Das Robert-Koch-Institut sucht dringend Studenten, die den örtliche Gesundheitsbehörden helfen, Kontakte von Covid19-Infizierten nachzuverfolgen: rki.de/DE/Content/Ser…

"Among my academic colleagues, I have observed a common response to the Covid-19 crisis. They are fighting valiantly for a sense of normalcy. I wish anyone who pursues that path the best of luck." chronicle.com/article/Why-Yo…

Fantastic work by my colleague, Mikolaj. Congrats Mikołaj Słabicki!!!

UCSC is looking for a manager for their CRISPR core: recruit.ucsc.edu/JPF00883

And another fantastic preprint from the Schulz lab! Congrats to all authors!!!

We are recruiting! #ERC-funded PhD (+postdoc) positions available in 2021 in #Berlin MPI for Molecular Genetics. Apply through our #IMPRS-BAC #PhD program. Computational and/or experimental projects available. Max Planck Society European Research Council (ERC)

We are recruiting! If you're interested in a PhD in the field of cancer research with a focus on drug target discovery using CRISPR technologies, please apply. More information at verwaltung.uni-halle.de/dezern3/Aussch…

Nature does open access

Please join us for an in-person seminar with Adrianos Skaros at the University of Halle-Wittenberg, this Wednesday at 4 pm.

Zusammenrücken, Kooperations-Potentiale aufdecken & wissenschaftlichen #Nachwuchs sichtbar machen: Mehr als 200 Teilnehmende nutzten den 8. #Forschungstag der Medizinischen Fakultät unimedhal Universität Halle (inaktiv), um die Ergebnisse ihrer #Forschung zu präsentieren. medizin.uni-halle.de/news/rueckblic…

New preprint together with Michael Boettcher! El Kassem et al: Targeted Perturb-seq Reveals EGR1 and FOS as Key Regulators of the Transcriptional RAF-MAPK Response biorxiv.org/content/10.110…