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"Leaving sticky notes for the children" - Here's a new "Dispatch" @EthanEwe and I wrote in Current Biology about the super cool discovery that Matthew Eroglu and Brent Derry had about transgenerational amyloids! (published recently in Nature Cell Biology) authors.elsevier.com/a/1kCED3QW8S6G…

This preprint is now published with some key additions guided by an excellent review process Nucleic Acids Res. Also grateful to our collaborators for helping progress this one across the finish line! susan clark Qian_Du Yael David Wanding Zhou and others! academic.oup.com/nar/advance-ar…

Scared to share this after 10 freaking years of waiting but here we go: We found that temperature *perception* can change the next generations, even when “it’s just in the parents' head”. Read how C. elegans neurons control epigenetic inheritance! biorxiv.org/content/10.110…

...and it doesn't end there: In a 2nd bioRxiv that we posted back-to-back with Björn Schumacher‘s lab we show that in addition to affecting epigenetic inheritance, temperature perception controls genetic inheritance via transposons! biorxiv.org/content/10.110…

Great highlight of our work but it is big team effort. I can’t take full credit for it :) onconaut.ai/about

📣 Hiring, please forward widely!! Two postdoc openings to work on genomics of diabetes 1. computational regulatory genomics/statistical genetics. 2. Experimental cell-based modeling DM if interested Centre for Genomic Regulation (CRG) shorturl.at/O3wMi shorturl.at/ieyZy

🚨 New paper alert 🚨 Our Human Microglia Atlas (HuMicA) characterizes #microglia subpopulations across 6 distinct #neurologic diseases. Ricardo Martins-Ferreira calafell Josep Carreras Leukaemia Research Institute (IJC) nature.com/articles/s4146…

Thrilled to share our milestone collaboration with Alán Aspuru-Guzik, Alex Zhavoronkov, Insilico Medicine, and our teams at UofT and the UAE! Using quantum computing to design KRAS inhibitors brings the future of drug discovery closer. Excited for what’s next!

Excited to share our #multiomics study of who was the world's #oldest living person! Our research on this record-breaking #supercentenarian suggests that, under certain conditions, #aging and #disease can become decoupled—challenging the common belief that they are inherently

Ever wondered how sperm are formed? Spermatogenesis is a microscopic marathon that starts in the testes and ends with fully functional sperm! Our new preprint biorxiv.org/content/10.110… takes a deep dive into zebrafish spermatogenesis, mapping out every fascinating step. 🧵👇 1/7

First seen in Biorxiv and now published and updated with more data in Nature Communications. With this work we have further enhanced CRISPR-Cas RNA targeting in vivo using transient approaches such as RNP or mRNA-gRNA in zebrafish embryos as vertebrate model. nature.com/articles/s4146…

Introducing cornetto, an adaptive genome assembly paradigm using Oxford Nanopore adaptive sampling. - greatly reduces cost per genome assembly - reference agnostic, so works for non-humans - assembly just using saliva - & many more Relies on 2 excellent software #readfish & #hifiasm.

Great pleasure to host Schübeler Lab this Friday - if in the Seville area, please join for what promises to be an incredible seminar!

Magnificent talk today at #CABDseminars by Dirk Schüleber! Dirk explained the studies of his team understanding how transcription factors work as sensors and modifiers of chromatin. Prof. Schübeler was hosted by Ozren Bogdanovic, one of the first lab members. Thanks for coming!

New preprint from the Lab at Cabimer. We present PLAMseq, using TurboID to do like ChIPseq and proximity proteomics in the same protocol with extra powers like mapping protein interactions in the genome. biorxiv.org/content/10.110…

A triumph of perseverance from twitterless Tom Weber, Christine Biben and the team, our in vivo barcoding "LoxCode mouse" used to resolve epiblast fate to fetal organs is finally published in Cell and available to import through The Jackson Laboratory sciencedirect.com/science/articl…

Finally out in Nature our collaboration with the Velten Lab 🥰 Enjoy the reading! nature.com/articles/s4158…

Save de date! Join us at Cabimer on October 17th for the Genoma Hub CSIC Workshop in "Genome Dynamics in Development and Disease". Slots available for talks! Registration opens soon!!

SWARM (Single-molecule Workflow for Analysing RNA Modifications) detects pseudouridine, m6A, and m5C on individual molecules from direct RNA nanopore signals (in both chemistries RNA002 and RNA004) github.com/comprna/SWARM see more on poster P2-396 at #rna2025 #RNA25 #RNAmods