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Suprachiasmatic nucleus promotes hyperglycemia induced by sleep delay: Current Biology cell.com/current-biolog…

Several colleagues have asked for our protocol for preparing low-input samples for single nucleus multiome (gene expression + ATAC) sequencing. It is now available on STAR Protocols (star-protocols.cell.com/protocols/3006) so that everyone can give it a try. 1/7

In a G0 cell, if Cohesin is continuously chugging along performing loop extrusion it must be going through a large amount of ATP. Does anyone have an idea how much of the cellular energy budget is dedicated to this process? @job_dekker Jesse Dixon Anders Sejr Hansen

I’m looking for examples where a gene is normally expressed in cell type A but a GWAS/QTL hit contains a variant that causes ectopic expression in cell type B. All examples welcome, plz RT! Jonathan Pritchard Veera Rajagopal  Sasha Gusev Daniel MacArthur Tuuli Lappalainen Anshul Kundaje (anshulkundaje@bluesky)

New GWAS study examines when a baby takes their first steps 🧬 ➡️ 🚼 ➡️ 🚶‍♀️ SNP based heritability, a lower bound of heritability calculated using only common variants, shows up at ~25%, much higher than I would have guessed. Work led by anna gui

A big congratulations to our #GWAS24 Poster Winners, Luis Eichelmann (Luis Eichelmann 🇪🇺) from Universität Lübeck & Brandon Logeman (Brandon Logeman) from Harvard University 🎉👏