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Are you still struggling with the manual curation of TEs? Do you want to know the magic of cleaning TE MSAs with only a single button click? Welcome to try TEtrimmer (paper will come soon) github.com/qjiangzhao/TEt… I am also looking forward to discussing this with you in #ICTE2024

Many #GenomeBrowsers only show one #genome assembly at a time. NCBI presents a new visualization tool called the #ComparativeGenomeViewer (#CGV) that aids in pairwise comparison of whole-genome eukaryotic assembly-assembly alignments #PLOSBiology plos.io/3QYDtUP

AlphaFold3 is out with improvements on structural models that include DNA/RNA and small molecules. Unfortunately, there is no code, no binary to run at scale and only a limited webserver. Why even publish? nature.com/articles/s4158…

We're excited to bring you the 2nd Journal Club of the month with Dr Brice Letcher! Brice Letcher He will explore how diverged lineages evolved in two cell-surface antigens of P. falciparum, adding important context to how malaria parasites evolve and spread sanger.zoom.us/webinar/regist…

This is the end of the world as we know it, if this is reproducible! The new era of functional modeling has begun. I took a transcription factor with an unknown structure and folded it with its recognition sequence embedded in longer DNA. AlphaFold3 accurately positioned the

This is a complex discussion that I am hoping will continue well beyond this letter. We need to find standards that work in an increasingly complex landscape of research and publishing, and that balances diverse interests. We need to find solutions that enable science to ...

👀This is a paper a lot of people have been waiting for: yes GPT-4 can help pick stocks, beating humans and other machine learning models trained for finance. The advantage is that it understands human narratives Also read the paragraph in the screenshot. papers.ssrn.com/sol3/papers.cf…

This is so clever

Thank you to everyone who attended our Journal Club with Dr Brice Letcher today! Brice Letcher If you missed the live session, a full recording is now available on our YouTube channel ⏯ youtube.com/watch?v=vubawp…

2021 rejection: “it will never work” 2022 rejection: “it will never work” 2023 rejection: “it will never work” 2024 rejection: “this has already been shown” 😂 nature.com/articles/d4158…

SAMD9 & SAMD9L are restriction factors of #poxviruses, what about other #viruses? Alexandre Legrand Lucie Etienne &co show that SAMD9L inhibits #HIV1 & other primate lentiviruses via a Schlafen-like active site, disrupting viral translation #PLOSBiology plos.io/4cn9ZZc

New paper! Our stick insects have weird chromosome segregation. The major centromere protein, CenH3, binds to the autosomes in a monocentric pattern, but in a holocentric pattern on the X. doi.org/10.1101/2024.0…

Wasn't sure to share it, but thought it might help someone. How I published 0 first-author papers in my 3yrs #postdoc -changed research topic -moved to a foreign country -#mentalhealth breakdown -existential crisis on my #academic career -#fellowship rejections -COVID

"Nematodes are the haiku among multicellular animals, combining endless variation with a deceptively simple underlying anatomical pattern." P. De Ley, Wormbook

lol who did this

The central dogma of molecular biology states that genetic information flows from DNA and RNA to protein, with reverse transcription converting RNA to DNA. In the pursuit of understanding how bacteria defend themselves from viral infection, two groups have found alternative

Just updated taxid-changelog. Now you can track each NCBI Taxonomy taxon's detailed changes in the past 10 years😮😱😃 This is the proudest work I've done in my past 10+ year academic career, cause it's useful and funny but no one else did this, haha. github.com/shenwei356/tax…

"Scooped"? We prefer to call it "complementary research," recognising its important role in reproducibility of science. Come to #PLOSBiology within 6 months of "scooping" and we'll consider it. See our new policy here: plos.io/2rRvTSA