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More data destroying Rx reps talking points. Already knew we SHOULD ✅ labs, one dose doesn’t fit all. Now issues w/ 💊💊interactions… Concomitant Drug Interactions With Non–Vitamin K Oral Anticoagulants Are Associated With Bleeding and Mortality Risk ahajournals.org/doi/10.1161/JA…

The relationship to surgery here is incredible! Like a discussion I had with my fellow last night on call. Or, for many out there, similar to the old adage of “ it takes five years to learn how and when to operate. it takes the rest of your career to learn when NOT to operate.“

Word

Yep. Guilty. Now add “and I’m at 30,000 feet” 😂😂😂 Shane Jensen Mike Van Gent Matt Leatherman, DO FACS kjkwinger6 Bellal Joseph Jonathan Meizoso, MD, MSPH, FACS Jessica Cardenas james

A swing and a miss for sevo...at least in patients with ARDS. Inhaled Sedation in Acute Respiratory Distress Syndrome jamanetwork.com/journals/jama/…

Their conclusion: no need for abx waiting on appy… My take: While no diff in perforation rates, ⬇️ SSI by 50% Role of Preoperative Antibiotic Treatment While Awaiting Appendectomy: The PERFECT-Antibiotics Randomized Clinical Trial | Infectious Diseases jamanetwork.com/journals/jamas…

We don’t use cell-saver (over-anticoagulated bag of RBCs w/ no plasma/platelets). However, 4 those that do, cellsaver clears most toluene/contaminants from surgical💨 Is surgical smoke a relevant contamination for salvaged autologous blood? A pilot study onlinelibrary.wiley.com/doi/epdf/10.11…

Mark Yazer closing out the first day of THOR 2025 with the 🎤 ⬇️ lecture. No, you do NOT have to leukoreduce WB.

26 hrs quicker to extubation, ⬇️ need 4 rescue 💊💊, but ⬆️ AEs w/ dex vs propofol Dexmedetomidine- or Clonidine-Based Sedation Compared With Propofol in Critically Ill Patients: The A2B Randomized Clinical Trial | Anesthesiology | JAMA | JAMA Network jamanetwork.com/journals/jama/…

Cold-stored platelets (CSP), not room temp platelets, conserved inherent function despite decreasing platelet counts through day 7. CSP also showed recruitment of other platelets through day 7 in this in vitro model frontiersin.org/journals/bioen…

“Smoother” induction w/ cipepofol vs. propofol in severe AS pts Hemodynamic Impact of Cipepofol vs Propofol During Anesthesia Induction in Patients With Severe Aortic Stenosis: A Randomized Clinical Trial | Anesthesiology | JAMA Surgery | JAMA Network jamanetwork.com/journals/jamas…

Ketamine gtt’s for the LOSS. Nice DB, RCT showing no benefit in severely injured pts. Actually stopped early for futility. Although, I must say I haven’t seen PCA’s used in our pts in 20 years… Journal of Trauma and Acute Care Surgery journals.lww.com/jtrauma/fullte…

What he said…👊👊👊

My V.A. pts used 2 tell me this, so I gave them coffee early on. Wish I woulda been smart enough 2 collect data! 😂 ⬇️ ⏰ flatus, ⬇️ LOS Coffee administration to promote return of bowel function after small bowel resection: A randomized, controlled trial americanjournalofsurgery.com/article/S0002-…