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Are you busy with #hepatology clinical work? Check out the clinical care points in this short and concise review on the cerebral effects of #cirrhosis and #portalhypertension from a group of International Society for Hepatic Encephalopathy members. Out now in Clinics in #LiverDisease. 👇 authors.elsevier.com/a/1i-BM_OnBPgg…

🟪NEW Article in press❕ Proton pump inhibitor use and risk of hepatic encephalopathy: a multicenter study 🔓#OpenAccess at 👉jhep-reports.eu/article/S2589-… #LiverTwitter #HepaticEncephalopathy

🔑Are all proteins🟰 for ammoniagenesis? No! 🔑Can one meal change affect ⬇️#ammonia in #cirrhosis? Yes! ✅our #RCT where 1⃣ meal change from 🥩to 🌱/🌿-based was enough to⬇️#ammonia ! 🔑Impt because replacing full diets⛔️ 🔑metabolomic changes ACG_CTG ⤵️ journals.lww.com/ctg/abstract/9…

There is no stepwise increase in the risk of encephalopathy with worsening psychometric scores in this international study journals.lww.com/hepcomm/fullte… Hepatology Communications Simon J. Gairing Patty Pringle Bloom, M.D. CLabenz

1+ 1 = 3 Lactulose + Rifaximin = Reduced episodes of hepatic encephalopathy journals.lww.com/hepcomm/fullte… Hepatology Communications

Brilliant State of the Art talk by @dthabut on hepatic encephalopathy 🤩 Love that HE is getting this spotlight EASLnews As the Professor stated: HE is the worst complication of cirrhosis We have a lot of work to do to improve this for our patients

Today EASLnews, Martin Kabelitz presents his poster about the impact of #TIPS on frailty: 💪 Frailty has the potential to improve after TIPS insertion 🏋🏽 Especially patients with a high degree of frailty show improvement SAT-090 #EASL2024

Mathias Jachs & the Non-Invasive CSPH Estimated Risk (NICER) model based on a contemporary cohort integrating SSM-100Hz 👏 👉 Developed in SLD & 🦠 suppression/cure 👉 Improved discrimination & calibration. 👉 It's just the NICER model, I guess! 😜 Thanks The Baveno Cooperation: an EASL Consortium!

WHAT'S AT STEAK IN NUTRITION FOR HEPATIC ENCEPHALOPATHY? No one had more fun than me and CLabenz writing this editorial: journals.lww.com/ctg/pages/arti… On Jasmohan Bajaj trial of meat vs veg burgers and ammonia: journals.lww.com/ctg/fulltext/2…

Let's start deprescribing all those superfluous PPI in cirrhosis patients‼️ jhep-reports.eu/article/S2589-… Multicenter study: no effect on HE, but only one-fourth of patients actually needed PPI JHEP Reports #LiverTwitter Why over-medicate people who already receive a bunch of 💊💊💊

"No value of non-selective beta-blockers after TIPS-insertion" published 'open access' at bit.ly/3AF9rjs #livertwitter #TIPS

Thrilled to have this work out in HEPATOLOGY Journal ! Short version: The problem - it’s hard to diagnose minimal HE or predict future overt HE in clinic What we found - automated speech analysis can do both

Non-Invasive CSPH Estimated Risk (NICER) model including Echosens SSM by VCTE at 100Hz 👉Developed (2020-2022) & validated (2023) in contemporary pts. 👉Outperforms ANTICIPATE(-NASH): AUC consistently >0.9. 👉Well-calibrated. 👉Sets a new standard IMHO. #LiverTwitter 🔗👇

We are very excited to bring the 8th ISHEN-T series with a potentially controversial topic! Join us and share your thoughts! The Roger Williams Institute of Liver Studies

❗QuickStroop for screening for minimal hepatic encephalopathy in patients with #cirrhosis 🔓#OpenAccess at 👉jhep-reports.eu/article/S2589-… #LiverTwitter

Today’s #readoftheweek📚discusses QuickStroop, which is a rapid screening tool to identify patients at risk for PHES-MHE, especially in patients below 60 years of age. Read here this JHEP Reports article: jhep-reports.eu/article/S2589-… 🙏CLabenz Simon J. Gairing Leonard Kaps Eva Maria Schleicher

💉 Albumin duration & AKI response in cirrhosis Eva M. Schleicher (Mainz) – #EASL2025 🕒 24h albumin new rule questioned 🏆 EASL AKI response definition wins 📈 20% of 24h NR improved at 48h ⚖️ Early vs late responders: Same mortality 🚨 Cr ↑ >16% @24h → terlipressin! 👇

📄 Full paper: journal-of-hepatology.eu/action/showPdf… 📚 Related paper challenging the 24h albumin new rule: pubmed.ncbi.nlm.nih.gov/40250764/ #EASL2025