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A new paper shows that personalized pancreatic cancer vaccines can keep patients cancer-free for YEARS - an incredible outcome for a cancer with only a 7% 5-year survival rate.

Study uncovers how low-carb diet drives colorectal cancer development temertymedicine.utoronto.ca/news/study-unc…

Thrilled to share new work led by Jie Yang in the lab published today in nature. We find that Aspirin prevents metastasis by releasing T cells from immune suppression by platelet TXA2. Cambridge University CRUK Cambridge Centre rdcu.be/eci1U

Linoleic acid is the most abundant polyunsaturated fatty acid in the Western-style diet and has been implicated in promoting inflammation and cancer. In Science, researchers report a mechanism by which linoleic acid can activate the mTORC1 protein kinase, which coordinates

🚨#WomensHealthNews: New discovery from Magee-Womens investigator Dr. Lan Coffman and colleagues at University of Pittsburgh identifies a novel trigger of a deadly form of ovarian cancer. Published in Cancer Discovery, the findings could lead to better approaches to prevent and detect the disease,

Exciting new study showing that the fatty acid Octanoic acid impacts breast epithelial cell metabolic-epigenetic crosstalk, priming cells towards an ERneg BC profile, along with a suspicious neural-like differentiation. Grateful to have played a small part! Congrats Mariana!

OCRA launches a global consortium with Ovarian Cancer Research Foundation (Australia), Ovarian Cancer Canada & Ovarian Cancer Action. Together, we’re funding a $1M+ grant in partnership with Microsoft’s AI for Good Lab (Microsoft Research): bit.ly/44XlsxK

Online now: Neurodevelopmental hijacking of oligodendrocyte lineage programs drives glioblastoma infiltration dlvr.it/TKpZcB

Excited to share our first lab paper, now published in Developmental Cell! 🧠 How do glioblastoma (GBM) cells invade the brain, and what enables them to spread so effectively?

Standing ovation at ⁦ASCO⁩ for the Challenge Trial. Take a look at this comparison of the magnitude of the exercise effect from Challenge versus multiple drug effects.

🚨🎉 Thrilled to share my first paper - now out in nature! Incredibly grateful to Javier Garcia-Bermudez for his mentorship and the support of our Children’s Research Institute at UT Southwestern community. Excited to keep pushing this work forward in the lab!

Nature research paper: Targeting GRPR for sex hormone-dependent cancer after loss of E-cadherin go.nature.com/449wj6V

I’m thrilled to share that the main work of my PhD has been published Cancer Cell! With Matthias Mann Lab & Ernst Lengyel, we analyzed the progression from ovarian serous borderline tumors to invasive cancer using spatial proteo-transcriptomics and identified new therapeutic targets.

In Science, researchers present a new method to safely and preferentially generate CAR T cells directly inside the body using targeted lipid nanoparticles that deliver mRNA directly to T cells. The approach showed rapid and sustained immune reprogramming in preclinical models,

METABOLIC MESSENGERS | Andrea Hevener & S Correa (David Geffen School of Medicine at UCLA) A comprehensive #overview of the preclinical and clinical evidence showing the metabolic role of #oestradiol and its receptors in both women and men. Read it here: rdcu.be/etXpG

I'm excited to announce that my lab is looking to hire a motivated Postdoctoral Associate at the University of Pittsburgh and UPMC Hillman Cancer Center. Interested in personalized prevention, therapeutics, and women's health research? 📢Learn more: cfopitt.taleo.net/careersection/…

So proud of this remarkable work from the Meisel lab UPMC Hillman Cancer Center Exercise-induced microbiota metabolite enhances CD8 T cell antitumor i... sciencedirect.com/science/articl…

So excited to share this with you all!😃Rama Khokha and I revisit a core assumption in cancer biology: is tumour heterogeneity a reflection of disorganization? Our thoughts on how self-organization shapes tumour tissues, and why that matters for oncology: nature.com/articles/s4156…